Abstract
Disease caused by the infections by Clostridium perfringens type B have been most frequently been reported in lambs, occasionally in calves, and very rarely in foals. This chapter discusses the etiology, clinical signs, diagnosis, and prevention and treatment of infections by C. perfringens type B. C. perfringens type B isolates carry the genes encoding beta (CPB) and epsilon (ETX) toxins, but different strains can also encode several other non-typing toxins. In young lambs, C. perfringens type B causes acute abdominal pain, a distended abdomen, and hemorrhagic diarrhea. There is multifocal to diffuse transmural hemorrhage of the small intestine, with mucosal coagulation necrosis that may extend to the muscularis and serosa. Final diagnosis relies on detection of both CPB and ETX in the intestinal content of affected animals, together with isolation of C. perfringens type B from the same specimen.
| Original language | English (US) |
|---|---|
| Title of host publication | Clostridial Diseases in Animals |
| Publisher | wiley |
| Pages | 139-142 |
| Number of pages | 4 |
| ISBN (Electronic) | 9781118728291 |
| ISBN (Print) | 9781118728406 |
| DOIs | |
| State | Published - Apr 8 2016 |
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Keywords
- Beta toxin
- C. perfringens Type B
- Epsilon toxin
- Transmural hemorrhage
ASJC Scopus subject areas
- veterinary(all)
Cite this
Infections by Clostridium perfringens Type B. / Uzal, Francisco A; Songer, J. Glenn.
Clostridial Diseases in Animals. wiley, 2016. p. 139-142.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Infections by Clostridium perfringens Type B
AU - Uzal, Francisco A
AU - Songer, J. Glenn
PY - 2016/4/8
Y1 - 2016/4/8
N2 - Disease caused by the infections by Clostridium perfringens type B have been most frequently been reported in lambs, occasionally in calves, and very rarely in foals. This chapter discusses the etiology, clinical signs, diagnosis, and prevention and treatment of infections by C. perfringens type B. C. perfringens type B isolates carry the genes encoding beta (CPB) and epsilon (ETX) toxins, but different strains can also encode several other non-typing toxins. In young lambs, C. perfringens type B causes acute abdominal pain, a distended abdomen, and hemorrhagic diarrhea. There is multifocal to diffuse transmural hemorrhage of the small intestine, with mucosal coagulation necrosis that may extend to the muscularis and serosa. Final diagnosis relies on detection of both CPB and ETX in the intestinal content of affected animals, together with isolation of C. perfringens type B from the same specimen.
AB - Disease caused by the infections by Clostridium perfringens type B have been most frequently been reported in lambs, occasionally in calves, and very rarely in foals. This chapter discusses the etiology, clinical signs, diagnosis, and prevention and treatment of infections by C. perfringens type B. C. perfringens type B isolates carry the genes encoding beta (CPB) and epsilon (ETX) toxins, but different strains can also encode several other non-typing toxins. In young lambs, C. perfringens type B causes acute abdominal pain, a distended abdomen, and hemorrhagic diarrhea. There is multifocal to diffuse transmural hemorrhage of the small intestine, with mucosal coagulation necrosis that may extend to the muscularis and serosa. Final diagnosis relies on detection of both CPB and ETX in the intestinal content of affected animals, together with isolation of C. perfringens type B from the same specimen.
KW - Beta toxin
KW - C. perfringens Type B
KW - Epsilon toxin
KW - Transmural hemorrhage
UR - http://www.scopus.com/inward/record.url?scp=85024890288&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85024890288&partnerID=8YFLogxK
U2 - 10.1002/9781118728291.ch11
DO - 10.1002/9781118728291.ch11
M3 - Chapter
AN - SCOPUS:85024890288
SN - 9781118728406
SP - 139
EP - 142
BT - Clostridial Diseases in Animals
PB - wiley
ER -