Infection with a novel gammaherpesvirus in northern elephant seals (Mirounga angustirostris)

Tracey Goldstein, Linda J Lowenstine, Thomas P. Lipscomb, Jonna A Mazet, Joseph Novak, Jeffrey L Stott, Frances M D Gulland

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Twenty juvenile northern elephant seals (Mirounga angustirostris) that died between 1998 and 2004 had ulcers on the tongue, palatine mucosa, and/or tonsils. Histologic examination of the lesions revealed cytoplasmic swelling, nuclear pyknosis, and eosinophilic to amphophilic intranuclear inclusions bodies suggestive of herpesviral infection. Electron microscopic examination and polymerase chain reaction analysis confirmed the presence of a herpesvirus. Subsequent DNA sequencing identified this to be a new gammaherpesvirus that was similar to Porcine lymphotropic virus 2, Alcephaline herpesvirus 1 (malignant catarrhal fever virus from wildebeest), and Chlorocebus rhadinovirus 1 from African green monkeys. Identical herpesviral DNA was also detected in blood and mucosal swabs collected from five healthy elephant seal pups.

Original languageEnglish (US)
Pages (from-to)830-835
Number of pages6
JournalJournal of Wildlife Diseases
Volume42
Issue number4
StatePublished - Oct 2006

Fingerprint

Earless Seals
Mirounga angustirostris
elephant
Rhadinovirus
virus
Herpesviridae
Alcelaphine herpesvirus 1
nuclear inclusions
Mirounga
Malignant Catarrh
wildebeest
DNA
Cercopithecus aethiops
tonsils
Infection
tongue
lesion
lesions (animal)
pups
infection

Keywords

  • Elephant seal
  • Gammaherpes-virus
  • Mirounga angustirostris
  • Ulcers

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Infection with a novel gammaherpesvirus in northern elephant seals (Mirounga angustirostris). / Goldstein, Tracey; Lowenstine, Linda J; Lipscomb, Thomas P.; Mazet, Jonna A; Novak, Joseph; Stott, Jeffrey L; Gulland, Frances M D.

In: Journal of Wildlife Diseases, Vol. 42, No. 4, 10.2006, p. 830-835.

Research output: Contribution to journalArticle

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