Infection studies in kittens, using feline infectious peritonitis virus propagated in cell culture.

N. C. Pedersen, J. F. Boyle, K. Floyd

Research output: Contribution to journalArticle

68 Scopus citations

Abstract

The propagation of feline infectious peritonitis virus (NW1-FIPV strain) in cell culture is described. Tissue culture-propagated virus was used to inoculate specific-pathogen-free kittens intraperitoneally, intratracheally, or orally. Intraperitoneal inoculation caused seroconversion and effusive peritonitis in 100% of the kittens. Intratracheal inoculation produced disease in 60% of the kittens, and oral inoculation in only 20%. Seroconversions without production of disease occurred in 10% of the kittens inoculated by either the intratracheal or the oral route. The remainder of the kittens inoculated by the intratracheal (30%) and oral (70%) routes did not develop serum antibodies or disease.

Original languageEnglish (US)
Pages (from-to)363-367
Number of pages5
JournalAmerican Journal of Veterinary Research
Volume42
Issue number3
StatePublished - Mar 1981

ASJC Scopus subject areas

  • veterinary(all)

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