Infants Born to Mothers with Clinical Chorioamnionitis: A Cross-Sectional Survey on the Use of Early-Onset Sepsis Risk Calculator and Prolonged Use of Antibiotics

Marina Ayrapetyan, David Carola, Satyanarayana Lakshminrusimha, Vineet Bhandari, Zubair H. Aghai

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective: To evaluate variations in practice for the management of neonates born to mothers with clinical chorioamnionitis. Methods: This was a prospective cross-sectional survey consisting of 10 multiple choice questionnaires distributed to 2,900 members of the Perinatal Section of American Academy of Pediatrics. Variations in responses were assessed and compared between the various groups. Results: A total of 682 members (23.5%) completed the survey; 169 (24.8%) indicated that they use the neonatal early-onset sepsis (EOS) risk calculator for the management of neonates born to mothers with clinical chorioamnionitis. More respondents from the western region of United States and level III units are using the EOS risk calculator compared with the south and level II units. Approximately 44% of the respondents indicated that they will not stop antibiotics at 48 to 72 hours in asymptomatic neonates born to mothers with chorioamnionitis with negative blood culture if the complete blood count (CBC) and C-reactive protein (CRP) are abnormal. Conclusion: A large number of practitioners are using the neonatal EOS risk calculator for neonates born to mothers with chorioamnionitis. Despite a clear guideline from the Committee on Fetus and Newborn, almost 44% will treat healthy-appearing neonates born to mothers with chorioamnionitis with a prolonged course of antibiotics solely for abnormal CBC or CRP.

Original languageEnglish (US)
Pages (from-to)428-433
Number of pages6
JournalAmerican Journal of Perinatology
Volume36
Issue number4
DOIs
StatePublished - Jan 1 2019

Fingerprint

Chorioamnionitis
Sepsis
Cross-Sectional Studies
Mothers
Newborn Infant
Anti-Bacterial Agents
Blood Cell Count
C-Reactive Protein
Practice Management
Risk Management
Fetus
Guidelines
Pediatrics
Surveys and Questionnaires

Keywords

  • EOS calculator
  • maternal fever
  • neonates
  • sepsis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Infants Born to Mothers with Clinical Chorioamnionitis : A Cross-Sectional Survey on the Use of Early-Onset Sepsis Risk Calculator and Prolonged Use of Antibiotics. / Ayrapetyan, Marina; Carola, David; Lakshminrusimha, Satyanarayana; Bhandari, Vineet; Aghai, Zubair H.

In: American Journal of Perinatology, Vol. 36, No. 4, 01.01.2019, p. 428-433.

Research output: Contribution to journalArticle

@article{1a71f9374ea243d6948e8c654afb5cf5,
title = "Infants Born to Mothers with Clinical Chorioamnionitis: A Cross-Sectional Survey on the Use of Early-Onset Sepsis Risk Calculator and Prolonged Use of Antibiotics",
abstract = "Objective: To evaluate variations in practice for the management of neonates born to mothers with clinical chorioamnionitis. Methods: This was a prospective cross-sectional survey consisting of 10 multiple choice questionnaires distributed to 2,900 members of the Perinatal Section of American Academy of Pediatrics. Variations in responses were assessed and compared between the various groups. Results: A total of 682 members (23.5{\%}) completed the survey; 169 (24.8{\%}) indicated that they use the neonatal early-onset sepsis (EOS) risk calculator for the management of neonates born to mothers with clinical chorioamnionitis. More respondents from the western region of United States and level III units are using the EOS risk calculator compared with the south and level II units. Approximately 44{\%} of the respondents indicated that they will not stop antibiotics at 48 to 72 hours in asymptomatic neonates born to mothers with chorioamnionitis with negative blood culture if the complete blood count (CBC) and C-reactive protein (CRP) are abnormal. Conclusion: A large number of practitioners are using the neonatal EOS risk calculator for neonates born to mothers with chorioamnionitis. Despite a clear guideline from the Committee on Fetus and Newborn, almost 44{\%} will treat healthy-appearing neonates born to mothers with chorioamnionitis with a prolonged course of antibiotics solely for abnormal CBC or CRP.",
keywords = "EOS calculator, maternal fever, neonates, sepsis",
author = "Marina Ayrapetyan and David Carola and Satyanarayana Lakshminrusimha and Vineet Bhandari and Aghai, {Zubair H.}",
year = "2019",
month = "1",
day = "1",
doi = "10.1055/s-0038-1668548",
language = "English (US)",
volume = "36",
pages = "428--433",
journal = "American Journal of Perinatology",
issn = "0735-1631",
publisher = "Thieme Medical Publishers",
number = "4",

}

TY - JOUR

T1 - Infants Born to Mothers with Clinical Chorioamnionitis

T2 - A Cross-Sectional Survey on the Use of Early-Onset Sepsis Risk Calculator and Prolonged Use of Antibiotics

AU - Ayrapetyan, Marina

AU - Carola, David

AU - Lakshminrusimha, Satyanarayana

AU - Bhandari, Vineet

AU - Aghai, Zubair H.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Objective: To evaluate variations in practice for the management of neonates born to mothers with clinical chorioamnionitis. Methods: This was a prospective cross-sectional survey consisting of 10 multiple choice questionnaires distributed to 2,900 members of the Perinatal Section of American Academy of Pediatrics. Variations in responses were assessed and compared between the various groups. Results: A total of 682 members (23.5%) completed the survey; 169 (24.8%) indicated that they use the neonatal early-onset sepsis (EOS) risk calculator for the management of neonates born to mothers with clinical chorioamnionitis. More respondents from the western region of United States and level III units are using the EOS risk calculator compared with the south and level II units. Approximately 44% of the respondents indicated that they will not stop antibiotics at 48 to 72 hours in asymptomatic neonates born to mothers with chorioamnionitis with negative blood culture if the complete blood count (CBC) and C-reactive protein (CRP) are abnormal. Conclusion: A large number of practitioners are using the neonatal EOS risk calculator for neonates born to mothers with chorioamnionitis. Despite a clear guideline from the Committee on Fetus and Newborn, almost 44% will treat healthy-appearing neonates born to mothers with chorioamnionitis with a prolonged course of antibiotics solely for abnormal CBC or CRP.

AB - Objective: To evaluate variations in practice for the management of neonates born to mothers with clinical chorioamnionitis. Methods: This was a prospective cross-sectional survey consisting of 10 multiple choice questionnaires distributed to 2,900 members of the Perinatal Section of American Academy of Pediatrics. Variations in responses were assessed and compared between the various groups. Results: A total of 682 members (23.5%) completed the survey; 169 (24.8%) indicated that they use the neonatal early-onset sepsis (EOS) risk calculator for the management of neonates born to mothers with clinical chorioamnionitis. More respondents from the western region of United States and level III units are using the EOS risk calculator compared with the south and level II units. Approximately 44% of the respondents indicated that they will not stop antibiotics at 48 to 72 hours in asymptomatic neonates born to mothers with chorioamnionitis with negative blood culture if the complete blood count (CBC) and C-reactive protein (CRP) are abnormal. Conclusion: A large number of practitioners are using the neonatal EOS risk calculator for neonates born to mothers with chorioamnionitis. Despite a clear guideline from the Committee on Fetus and Newborn, almost 44% will treat healthy-appearing neonates born to mothers with chorioamnionitis with a prolonged course of antibiotics solely for abnormal CBC or CRP.

KW - EOS calculator

KW - maternal fever

KW - neonates

KW - sepsis

UR - http://www.scopus.com/inward/record.url?scp=85062430890&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85062430890&partnerID=8YFLogxK

U2 - 10.1055/s-0038-1668548

DO - 10.1055/s-0038-1668548

M3 - Article

C2 - 30130819

AN - SCOPUS:85062430890

VL - 36

SP - 428

EP - 433

JO - American Journal of Perinatology

JF - American Journal of Perinatology

SN - 0735-1631

IS - 4

ER -