Incremental intravenous nitroglycerin for control of afterload during anesthesia in patients undergoing myocardial revascularization

K. B. Stengert, B. L. Wilsey, E. J. Hurley, T. M. Grehl, A. J. Lurie, R. C. Klein, L. R. Upjohn

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

In 25 patients undergoing coronary artery bypass grafting hemodynamic measurements (including values obtained with Swan-Ganz catheterization in 21 of the patients) were made before and after administering a bolus injection of 64 or 96 mcg of nitroglycerin to relieve intraoperative hypertension. This pharmacological agent reduced afterload and preload without raising heart rate. The effect was apparent within 1-3 min and lasted 5-10 min. Untoward hypotension was not encountered in any instance. This intervention appears to be a safe approach to the treatment of intraoperative hypertension in patients with coronary artery disease.

Original languageEnglish (US)
Pages (from-to)223-227
Number of pages5
JournalAnaesthesist
Volume27
Issue number5
StatePublished - 1978

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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