Increased prevalence of the metabolic syndrome in patients with psoriatic arthritis

Smriti K. Raychaudhuri, Sidhartha Chatterjee, Caroline Nguyen, Manpreet Kaur, Ishwarlal Jialal, Siba P Raychaudhuri

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Objectives: Psoriasis (PsO) is a common chronic T cell-mediated inflammatory disorder traditionally thought to manifest in the skin and joints (psoriatic arthritis, PsA). Recently, it has been shown that these patients have an increased risk for myocardial infarction and this was greater with increasing severity of psoriasis. Patients with psoriasis have reported to have cardiometabolic disturbances including obesity, insulin resistance, and dyslipidemia. This constellation of risk factors, referred to as the metabolic syndrome, increases the risk for atherosclerotic cardiovascular disease (ASCVD) and type 2 diabetes mellitus. The aim of this study was to determine the prevalence of metabolic syndrome in PsA. Methods: In our study, we examined the records of 105 patients with PsA to determine the prevalence of metabolic syndrome in PsA. This was a retrospective analysis of the Sacramento Veterans Affairs database. Results: Our results demonstrated an increased prevalence of the metabolic syndrome in patients with PsA (61/105 patients or 58.1%) compared to the 35.2 % reported for the Third National Health and Nutrition Examination Survery (NHANES III) data. Conclusions: Thus, patients with PsA have a very high prevalence of metabolic syndrome, which predisposes them to an increased risk of both diabetes and ASCVD.

Original languageEnglish (US)
Pages (from-to)331-334
Number of pages4
JournalMetabolic Syndrome and Related Disorders
Volume8
Issue number4
DOIs
StatePublished - Aug 1 2010

Fingerprint

Psoriatic Arthritis
Psoriasis
Cardiovascular Diseases
Nutrition Surveys
Veterans
Dyslipidemias
Type 2 Diabetes Mellitus
Insulin Resistance
Obesity
Joints
Myocardial Infarction
Databases
T-Lymphocytes
Skin
Health

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Increased prevalence of the metabolic syndrome in patients with psoriatic arthritis. / Raychaudhuri, Smriti K.; Chatterjee, Sidhartha; Nguyen, Caroline; Kaur, Manpreet; Jialal, Ishwarlal; Raychaudhuri, Siba P.

In: Metabolic Syndrome and Related Disorders, Vol. 8, No. 4, 01.08.2010, p. 331-334.

Research output: Contribution to journalArticle

Raychaudhuri, Smriti K. ; Chatterjee, Sidhartha ; Nguyen, Caroline ; Kaur, Manpreet ; Jialal, Ishwarlal ; Raychaudhuri, Siba P. / Increased prevalence of the metabolic syndrome in patients with psoriatic arthritis. In: Metabolic Syndrome and Related Disorders. 2010 ; Vol. 8, No. 4. pp. 331-334.
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