Abstract
Objectives: Psoriasis (PsO) is a common chronic T cell-mediated inflammatory disorder traditionally thought to manifest in the skin and joints (psoriatic arthritis, PsA). Recently, it has been shown that these patients have an increased risk for myocardial infarction and this was greater with increasing severity of psoriasis. Patients with psoriasis have reported to have cardiometabolic disturbances including obesity, insulin resistance, and dyslipidemia. This constellation of risk factors, referred to as the metabolic syndrome, increases the risk for atherosclerotic cardiovascular disease (ASCVD) and type 2 diabetes mellitus. The aim of this study was to determine the prevalence of metabolic syndrome in PsA. Methods: In our study, we examined the records of 105 patients with PsA to determine the prevalence of metabolic syndrome in PsA. This was a retrospective analysis of the Sacramento Veterans Affairs database. Results: Our results demonstrated an increased prevalence of the metabolic syndrome in patients with PsA (61/105 patients or 58.1%) compared to the 35.2 % reported for the Third National Health and Nutrition Examination Survery (NHANES III) data. Conclusions: Thus, patients with PsA have a very high prevalence of metabolic syndrome, which predisposes them to an increased risk of both diabetes and ASCVD.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 331-334 |
| Number of pages | 4 |
| Journal | Metabolic Syndrome and Related Disorders |
| Volume | 8 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 1 2010 |
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ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Internal Medicine
Cite this
Increased prevalence of the metabolic syndrome in patients with psoriatic arthritis. / Raychaudhuri, Smriti K.; Chatterjee, Sidhartha; Nguyen, Caroline; Kaur, Manpreet; Jialal, Ishwarlal; Raychaudhuri, Siba P.
In: Metabolic Syndrome and Related Disorders, Vol. 8, No. 4, 01.08.2010, p. 331-334.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Increased prevalence of the metabolic syndrome in patients with psoriatic arthritis
AU - Raychaudhuri, Smriti K.
AU - Chatterjee, Sidhartha
AU - Nguyen, Caroline
AU - Kaur, Manpreet
AU - Jialal, Ishwarlal
AU - Raychaudhuri, Siba P
PY - 2010/8/1
Y1 - 2010/8/1
N2 - Objectives: Psoriasis (PsO) is a common chronic T cell-mediated inflammatory disorder traditionally thought to manifest in the skin and joints (psoriatic arthritis, PsA). Recently, it has been shown that these patients have an increased risk for myocardial infarction and this was greater with increasing severity of psoriasis. Patients with psoriasis have reported to have cardiometabolic disturbances including obesity, insulin resistance, and dyslipidemia. This constellation of risk factors, referred to as the metabolic syndrome, increases the risk for atherosclerotic cardiovascular disease (ASCVD) and type 2 diabetes mellitus. The aim of this study was to determine the prevalence of metabolic syndrome in PsA. Methods: In our study, we examined the records of 105 patients with PsA to determine the prevalence of metabolic syndrome in PsA. This was a retrospective analysis of the Sacramento Veterans Affairs database. Results: Our results demonstrated an increased prevalence of the metabolic syndrome in patients with PsA (61/105 patients or 58.1%) compared to the 35.2 % reported for the Third National Health and Nutrition Examination Survery (NHANES III) data. Conclusions: Thus, patients with PsA have a very high prevalence of metabolic syndrome, which predisposes them to an increased risk of both diabetes and ASCVD.
AB - Objectives: Psoriasis (PsO) is a common chronic T cell-mediated inflammatory disorder traditionally thought to manifest in the skin and joints (psoriatic arthritis, PsA). Recently, it has been shown that these patients have an increased risk for myocardial infarction and this was greater with increasing severity of psoriasis. Patients with psoriasis have reported to have cardiometabolic disturbances including obesity, insulin resistance, and dyslipidemia. This constellation of risk factors, referred to as the metabolic syndrome, increases the risk for atherosclerotic cardiovascular disease (ASCVD) and type 2 diabetes mellitus. The aim of this study was to determine the prevalence of metabolic syndrome in PsA. Methods: In our study, we examined the records of 105 patients with PsA to determine the prevalence of metabolic syndrome in PsA. This was a retrospective analysis of the Sacramento Veterans Affairs database. Results: Our results demonstrated an increased prevalence of the metabolic syndrome in patients with PsA (61/105 patients or 58.1%) compared to the 35.2 % reported for the Third National Health and Nutrition Examination Survery (NHANES III) data. Conclusions: Thus, patients with PsA have a very high prevalence of metabolic syndrome, which predisposes them to an increased risk of both diabetes and ASCVD.
UR - http://www.scopus.com/inward/record.url?scp=77955586673&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77955586673&partnerID=8YFLogxK
U2 - 10.1089/met.2009.0124
DO - 10.1089/met.2009.0124
M3 - Article
C2 - 20367239
AN - SCOPUS:77955586673
VL - 8
SP - 331
EP - 334
JO - Metabolic Syndrome and Related Disorders
JF - Metabolic Syndrome and Related Disorders
SN - 1540-4196
IS - 4
ER -