Increased Galectin-1 Expression in Thymic Epithelial Tumors

Jonathan Riess; Christina S. Kong; Robert B. West; Sukhmani K. Padda; Joel W. Neal; Heather A. Wakelee; Quynh Thu Le

doi:10.1016/j.cllc.2018.12.005

Increased Galectin-1 Expression in Thymic Epithelial Tumors

Jonathan Riess, Christina S. Kong, Robert B. West, Sukhmani K. Padda, Joel W. Neal, Heather A. Wakelee, Quynh Thu Le

Hematology and Oncology

Research output: Contribution to journal › Article

1 Scopus citations

Abstract

Thymic malignancies are rare tumors where lack of preclinical models adversely affect development of new therapies. Galectin-1 is an important protein in cancer involved in maintaining an immunosuppressive environment. This study examined galectin-1 expression in a large thymic epithelial tumor issue microarray and found elevated expression compared to benign thymus controls. Galectin-1 is a potential therapeutic target in thymic malignancies.

Original language	English (US)
Journal	Clinical Lung Cancer
DOIs	https://doi.org/10.1016/j.cllc.2018.12.005
State	Published - Jan 1 2019

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Keywords

Thymic malignancy
Tumor microenvironment

ASJC Scopus subject areas

Oncology
Pulmonary and Respiratory Medicine
Cancer Research

Cite this

Riess, J., Kong, C. S., West, R. B., Padda, S. K., Neal, J. W., Wakelee, H. A., & Le, Q. T. (2019). Increased Galectin-1 Expression in Thymic Epithelial Tumors. Clinical Lung Cancer. https://doi.org/10.1016/j.cllc.2018.12.005

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10.1016/j.cllc.2018.12.005