The histocompatibility antigen, HL A8, was found to be elevated in patients with Sjogren's syndrome. Among 28 patients, the frequency of HL A8 was 58% compared to 21% among controls (P<0.001 after correction). With the addition of this disorder to the list of other autoimmune diseases associated with HL A8, it now seems possible to postulate a single basis autoimmune defect gene in high linkage disequilibrium with HL A8.
|Original language||English (US)|
|Number of pages||5|
|State||Published - 1975|
ASJC Scopus subject areas
- Cell Biology