Increased frequency of HL A8 in Sjogren's syndrome

M. Eric Gershwin, P. I. Terasaki, R. Graw, T. M. Chused

Research output: Contribution to journalArticle

38 Scopus citations


The histocompatibility antigen, HL A8, was found to be elevated in patients with Sjogren's syndrome. Among 28 patients, the frequency of HL A8 was 58% compared to 21% among controls (P<0.001 after correction). With the addition of this disorder to the list of other autoimmune diseases associated with HL A8, it now seems possible to postulate a single basis autoimmune defect gene in high linkage disequilibrium with HL A8.

Original languageEnglish (US)
Pages (from-to)342-346
Number of pages5
JournalTissue Antigens
Issue number5
StatePublished - 1975
Externally publishedYes


ASJC Scopus subject areas

  • Cell Biology
  • Immunology

Cite this

Gershwin, M. E., Terasaki, P. I., Graw, R., & Chused, T. M. (1975). Increased frequency of HL A8 in Sjogren's syndrome. Tissue Antigens, 6(5), 342-346.