Incompatibility between bacteriophage lambda and the sex factor F

Michael German, Michael Syvanen

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Defective lambda plasmids, either λdv or λN, interfere with the replication of the Escherichia coli sex factor F. The incompatibility between these two plasmids is considered due to the P protein of lambda, since non-lambda replicons into which the lambda P gene has been cloned inhibit F replication. The inhibitory effect of the P protein on F replication is reduced in bacteria with the dnaB mutation grpB. This implies that the interference by lambda P protein is mediated, at least in part, through the E. coli dnaB product.

Original languageEnglish (US)
Pages (from-to)207-210
Number of pages4
Issue number2
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology


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