Abstract
Introduction: Little is known about dementia incidence in diverse populations of oldest-old, the age group with highest dementia incidence. Methods: Incident dementia diagnoses from 1/1/2010 to 9/30/2015 were abstracted from medical records for 2350 members of an integrated health care system in California (n = 1702 whites, n = 375 blacks, n = 105 Latinos, n = 168 Asians) aged ≥90 in 2010. We estimated race/ethnicity-specific age-adjusted dementia incidence rates and implemented Cox proportional hazards models and Fine and Gray competing risk of death models adjusted for demographics and comorbidities in midlife and late-life. Results: Dementia incidence rates (n = 771 cases) were lowest among Asians (89.9/1000 person-years), followed by whites (96.9/1000 person-years), Latinos (105.8/1000 person-years), and blacks (121.5/1000 person-years). Cox regression and competing risk models estimated 28% and 36% higher dementia risk for blacks versus whites adjusting for demographics and comorbidities. Discussion: Patterns of racial/ethnic disparities in dementia seen in younger older adults continue after the age of 90 years, though smaller in magnitude.
Original language | English (US) |
---|---|
Pages (from-to) | 497-505 |
Number of pages | 9 |
Journal | Alzheimer's and Dementia |
Volume | 15 |
Issue number | 4 |
DOIs | |
State | Published - Apr 1 2019 |
Keywords
- Dementia
- Disparities
- Epidemiology
- Ethnicity
- Oldest-old
- Race
ASJC Scopus subject areas
- Epidemiology
- Health Policy
- Developmental Neuroscience
- Clinical Neurology
- Geriatrics and Gerontology
- Cellular and Molecular Neuroscience
- Psychiatry and Mental health