Incidence of contrast-induced nephropathy after renal graft catheter arteriography using iodine-based contrast medium

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Abstract

OBJECTIVE: The objective of our study was to assess the incidence of contrast-induced nephropathy (CIN), dialysis, and graft loss after direct intraarterial infusion of iodine-based contrast medium (CM) in renal allograft recipients. MATERIALS AND METHODS: One hundred patients underwent renal graft catheter arteriography between 2006 and 2014. CIN was defined as an increase in serum creatinine value of 0.5 mg/dL or more above the creatinine value before arteriography. CIN could be assessed in 37 patients with creatinine levels obtained before arteriography and 24-72 hours after arteriography. Dialysis requirement and renal allograft loss at 30 days after the procedure were recorded in all 100 patients. RESULTS: In the 37 patients who could be assessed for CIN, three patients (8%) met the criteria for CIN. In a subgroup analysis, there was an increased incidence of CIN in patients undergoing angiography alone (25%) compared with those in the angioplasty and stenting group (0%) (p = 0.028). At 30 days after the procedure, none (0/100) of the patients required dialysis or had graft failure. CONCLUSION: In a cohort of patients with a single renal allograft undergoing renal graft catheter arteriography using iodine-based CM, the overall incidence of CIN was low and no major adverse outcomes were noted at 30 days after the procedure. However, in a subgroup analysis, the patients who underwent arteriography alone-that is, without angioplasty or stenting-had a statistically significant higher rate of CIN.

Original languageEnglish (US)
Pages (from-to)783-786
Number of pages4
JournalAmerican Journal of Roentgenology
Volume206
Issue number4
DOIs
StatePublished - Apr 1 2016

Fingerprint

Iodine
Contrast Media
Angiography
Catheters
Transplants
Kidney
Incidence
Allografts
Creatinine
Angioplasty
Dialysis
Intra Arterial Infusions
Renal Dialysis
Serum

Keywords

  • Angiography
  • Contrast-induced nephropathy
  • Nephrotoxicity
  • Renal transplant

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

@article{c7c8d229c7ee44e0abe41781c03fbf45,
title = "Incidence of contrast-induced nephropathy after renal graft catheter arteriography using iodine-based contrast medium",
abstract = "OBJECTIVE: The objective of our study was to assess the incidence of contrast-induced nephropathy (CIN), dialysis, and graft loss after direct intraarterial infusion of iodine-based contrast medium (CM) in renal allograft recipients. MATERIALS AND METHODS: One hundred patients underwent renal graft catheter arteriography between 2006 and 2014. CIN was defined as an increase in serum creatinine value of 0.5 mg/dL or more above the creatinine value before arteriography. CIN could be assessed in 37 patients with creatinine levels obtained before arteriography and 24-72 hours after arteriography. Dialysis requirement and renal allograft loss at 30 days after the procedure were recorded in all 100 patients. RESULTS: In the 37 patients who could be assessed for CIN, three patients (8{\%}) met the criteria for CIN. In a subgroup analysis, there was an increased incidence of CIN in patients undergoing angiography alone (25{\%}) compared with those in the angioplasty and stenting group (0{\%}) (p = 0.028). At 30 days after the procedure, none (0/100) of the patients required dialysis or had graft failure. CONCLUSION: In a cohort of patients with a single renal allograft undergoing renal graft catheter arteriography using iodine-based CM, the overall incidence of CIN was low and no major adverse outcomes were noted at 30 days after the procedure. However, in a subgroup analysis, the patients who underwent arteriography alone-that is, without angioplasty or stenting-had a statistically significant higher rate of CIN.",
keywords = "Angiography, Contrast-induced nephropathy, Nephrotoxicity, Renal transplant",
author = "Ghaneh Fananapazir and Christoph Troppmann and Corwin, {Michael T} and Bent, {Chris K.} and Vu, {Catherine T} and Ramit Lamba",
year = "2016",
month = "4",
day = "1",
doi = "10.2214/AJR.15.15501",
language = "English (US)",
volume = "206",
pages = "783--786",
journal = "American Journal of Roentgenology",
issn = "0361-803X",
publisher = "American Roentgen Ray Society",
number = "4",

}

TY - JOUR

T1 - Incidence of contrast-induced nephropathy after renal graft catheter arteriography using iodine-based contrast medium

AU - Fananapazir, Ghaneh

AU - Troppmann, Christoph

AU - Corwin, Michael T

AU - Bent, Chris K.

AU - Vu, Catherine T

AU - Lamba, Ramit

PY - 2016/4/1

Y1 - 2016/4/1

N2 - OBJECTIVE: The objective of our study was to assess the incidence of contrast-induced nephropathy (CIN), dialysis, and graft loss after direct intraarterial infusion of iodine-based contrast medium (CM) in renal allograft recipients. MATERIALS AND METHODS: One hundred patients underwent renal graft catheter arteriography between 2006 and 2014. CIN was defined as an increase in serum creatinine value of 0.5 mg/dL or more above the creatinine value before arteriography. CIN could be assessed in 37 patients with creatinine levels obtained before arteriography and 24-72 hours after arteriography. Dialysis requirement and renal allograft loss at 30 days after the procedure were recorded in all 100 patients. RESULTS: In the 37 patients who could be assessed for CIN, three patients (8%) met the criteria for CIN. In a subgroup analysis, there was an increased incidence of CIN in patients undergoing angiography alone (25%) compared with those in the angioplasty and stenting group (0%) (p = 0.028). At 30 days after the procedure, none (0/100) of the patients required dialysis or had graft failure. CONCLUSION: In a cohort of patients with a single renal allograft undergoing renal graft catheter arteriography using iodine-based CM, the overall incidence of CIN was low and no major adverse outcomes were noted at 30 days after the procedure. However, in a subgroup analysis, the patients who underwent arteriography alone-that is, without angioplasty or stenting-had a statistically significant higher rate of CIN.

AB - OBJECTIVE: The objective of our study was to assess the incidence of contrast-induced nephropathy (CIN), dialysis, and graft loss after direct intraarterial infusion of iodine-based contrast medium (CM) in renal allograft recipients. MATERIALS AND METHODS: One hundred patients underwent renal graft catheter arteriography between 2006 and 2014. CIN was defined as an increase in serum creatinine value of 0.5 mg/dL or more above the creatinine value before arteriography. CIN could be assessed in 37 patients with creatinine levels obtained before arteriography and 24-72 hours after arteriography. Dialysis requirement and renal allograft loss at 30 days after the procedure were recorded in all 100 patients. RESULTS: In the 37 patients who could be assessed for CIN, three patients (8%) met the criteria for CIN. In a subgroup analysis, there was an increased incidence of CIN in patients undergoing angiography alone (25%) compared with those in the angioplasty and stenting group (0%) (p = 0.028). At 30 days after the procedure, none (0/100) of the patients required dialysis or had graft failure. CONCLUSION: In a cohort of patients with a single renal allograft undergoing renal graft catheter arteriography using iodine-based CM, the overall incidence of CIN was low and no major adverse outcomes were noted at 30 days after the procedure. However, in a subgroup analysis, the patients who underwent arteriography alone-that is, without angioplasty or stenting-had a statistically significant higher rate of CIN.

KW - Angiography

KW - Contrast-induced nephropathy

KW - Nephrotoxicity

KW - Renal transplant

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U2 - 10.2214/AJR.15.15501

DO - 10.2214/AJR.15.15501

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JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

SN - 0361-803X

IS - 4

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