Incidence, Nature, and Etiology of Metabolic Acidosis in Dogs and Cats

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Background: Metabolic acidosis is an important abnormality in ill and injured dogs and cats. Objectives: To describe the incidence, nature, and etiology of metabolic acidosis in dogs and cats that had arterial or venous blood gases measured for any reason at a university teaching hospital. Animals: Dogs and cats at the Veterinary Medical Teaching Hospital. Methods: Acid base parameters and electrolyte and lactate concentrations in dogs and cats measured during a 13-month period were retrospectively retrieved from a computer database. Metabolic acidosis was defined as a standardized base excess (SBE) in dogs of <-4 mmol/L and in cats <-5 mmol/L. Results: A total of 1,805 dogs and cats were included; of these, 887 (49%) were classified as having a metabolic acidosis (753 dogs and 134 cats). Primary metabolic acidosis was the most common disorder in dogs, whereas mixed acid base disorder of metabolic acidosis and respiratory acidosis was most common in cats. Hyperchloremic metabolic acidosis was more common than a high anion gap (AG) metabolic acidosis; 25% of dogs and 34% of cats could not be classified as having either a hyperchloremic metabolic acidosis or a high AG metabolic acidosis. Conclusions and Clinical Importance: Metabolic acidosis was found commonly in this patient population and was associated with a wide variety of disease processes. Mixed acid base disorders occur frequently and routine categorization of metabolic acidosis based on the presence of high AG or hyperchloremia may be misleading in a large proportion of cases.

Original languageEnglish (US)
Pages (from-to)1107-1114
Number of pages8
JournalJournal of Veterinary Internal Medicine
Volume26
Issue number5
DOIs
StatePublished - Sep 2012

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acidosis
Acidosis
etiology
Cats
Dogs
cats
incidence
dogs
Incidence
Acid-Base Equilibrium
anions
Teaching Hospitals
Acids
acids
Respiratory Acidosis
blood gases
Electrolytes
Lactic Acid
electrolytes
lactates

Keywords

  • Anion gap
  • Base excess
  • Bicarbonate
  • Hyperchloremia

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Incidence, Nature, and Etiology of Metabolic Acidosis in Dogs and Cats. / Hopper, Katrina; Epstein, Steven E.

In: Journal of Veterinary Internal Medicine, Vol. 26, No. 5, 09.2012, p. 1107-1114.

Research output: Contribution to journalArticle

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