Abstract
We present in vivo volumetric depth-resolved vasculature images of the anterior segment of the human eye acquired with phase-variance based motion contrast using a high-speed (100 kHz, 10<sup>5</sup> A-scans/s) swept source optical coherence tomography system (SSOCT). High phase stability SSOCT imaging was achieved by using a computationally efficient phase stabilization approach. The human corneo-scleral junction and sclera were imaged with swept source phase-variance optical coherence angiography and compared with slit lamp images from the same eyes of normal subjects. Different features of the rich vascular system in the conjunctiva and episclera were visualized and described. This system can be used as a potential tool for ophthalmological research to determine changes in the outflow system, which may be helpful for identification of abnormalities that lead to glaucoma.
| Original language | English (US) |
|---|---|
| Article number | 065301 |
| Journal | Journal of Optics (United Kingdom) |
| Volume | 17 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1 2015 |
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Keywords
- imaging systems
- medical and biological imaging
- ophthalmology
- optical coherence tomography
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
Cite this
In vivo volumetric depth-resolved vasculature imaging of human limbus and sclera with 1 μm swept source phase-variance optical coherence angiography. / Poddar, Raju; Zawadzki, Robert; Cortés, Dennis E.; Mannis, Mark J; Werner, John S.
In: Journal of Optics (United Kingdom), Vol. 17, No. 6, 065301, 01.06.2015.Research output: Contribution to journal › Article
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TY - JOUR
T1 - In vivo volumetric depth-resolved vasculature imaging of human limbus and sclera with 1 μm swept source phase-variance optical coherence angiography
AU - Poddar, Raju
AU - Zawadzki, Robert
AU - Cortés, Dennis E.
AU - Mannis, Mark J
AU - Werner, John S
PY - 2015/6/1
Y1 - 2015/6/1
N2 - We present in vivo volumetric depth-resolved vasculature images of the anterior segment of the human eye acquired with phase-variance based motion contrast using a high-speed (100 kHz, 105 A-scans/s) swept source optical coherence tomography system (SSOCT). High phase stability SSOCT imaging was achieved by using a computationally efficient phase stabilization approach. The human corneo-scleral junction and sclera were imaged with swept source phase-variance optical coherence angiography and compared with slit lamp images from the same eyes of normal subjects. Different features of the rich vascular system in the conjunctiva and episclera were visualized and described. This system can be used as a potential tool for ophthalmological research to determine changes in the outflow system, which may be helpful for identification of abnormalities that lead to glaucoma.
AB - We present in vivo volumetric depth-resolved vasculature images of the anterior segment of the human eye acquired with phase-variance based motion contrast using a high-speed (100 kHz, 105 A-scans/s) swept source optical coherence tomography system (SSOCT). High phase stability SSOCT imaging was achieved by using a computationally efficient phase stabilization approach. The human corneo-scleral junction and sclera were imaged with swept source phase-variance optical coherence angiography and compared with slit lamp images from the same eyes of normal subjects. Different features of the rich vascular system in the conjunctiva and episclera were visualized and described. This system can be used as a potential tool for ophthalmological research to determine changes in the outflow system, which may be helpful for identification of abnormalities that lead to glaucoma.
KW - imaging systems
KW - medical and biological imaging
KW - ophthalmology
KW - optical coherence tomography
UR - http://www.scopus.com/inward/record.url?scp=84930959909&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84930959909&partnerID=8YFLogxK
U2 - 10.1088/2040-8978/17/6/065301
DO - 10.1088/2040-8978/17/6/065301
M3 - Article
AN - SCOPUS:84930959909
VL - 17
JO - Journal of Optics (United Kingdom)
JF - Journal of Optics (United Kingdom)
SN - 2040-8978
IS - 6
M1 - 065301
ER -