In vivo testing of a prototype system providing simultaneous white light and near infrared autofluorescence image acquisition for detection of bladder cancer

Michael C. Jacobson, Ralph Devere White, Stavros G Demos

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

A prototype instrument developed to provide simultaneously ordinary visual endoscopy together with near infrared (NIR) autofluorescence imaging via parallel image acquisition is demonstrated. The two images are recorded concurrently and the instrument interfaces with any ordinary endoscope. Preliminary results of a pilot study focused on imaging of bladder tumors in vivo using this instrumentation are presented. The experimental results demonstrate the capabilities of this instrumentation design, imaging methodology, and define the current limitation for further development of the system.

Original languageEnglish (US)
Article number036011
JournalJournal of Biomedical Optics
Volume17
Issue number3
DOIs
StatePublished - Mar 2012

Keywords

  • Biomedical optics
  • Biophotonics
  • Endoscopy

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

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