In-vivo argon laser vascular welding using thermal feedback

Open- and closed-loop patency and collagen crosslinking

Ward Small IV, Peter M. Celliers, George E. Kopchok, Karen M. Reiser, Nicholas J. Heredia, Duncan J. Maitland, David C. Eder, Richard A. London, Mauricio Heilbron, Farabi Hussain, Rodney A. White, Luiz B. Da Silva, Dennis L Matthews

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

An in vivo study of vascular welding with a fiber-delivered argon laser was conducted using a canine model. Longitudinal arteriotomies and venotomies were treated on femoral vein and artery. Laser energy was delivered to the vessel wall via a 400 micrometer optical fiber. The surface temperature at the center of the laser spot was monitored in real time using a hollow glass optical fiber-based two-color infrared thermometer. The surface temperature was limited by either a room-temperature saline drip or direct feedback control of the laser using a mechanical shutter to alternately pass and block the laser. Acute patency was evaluated either visually (leak/no leak) or by in vivo burst pressure measurements. Biochemical assays were performed to investigate the possible laser-induced formation or destruction of enzymatically mediated covalent crosslinks between collagen molecules. Viable welds were created both with and without the use of feedback control. Tissues maintained at 50 degrees Celsius using feedback control had an elevated crosslink count compared to controls, while those irradiated without feedback control experienced a decrease. Differences between the volumetric heating associated with open and closed loop protocols may account for the different effects on collagen crosslinks. Covalent mechanisms may play a role in argon laser vascular fusion.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
Pages252-256
Number of pages5
Volume2970
DOIs
StatePublished - 1997
Externally publishedYes
EventLasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII - San Jose, CA, United States
Duration: Feb 8 1997Feb 8 1997

Other

OtherLasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII
CountryUnited States
CitySan Jose, CA
Period2/8/972/8/97

Fingerprint

Argon lasers
argon lasers
Collagen
crosslinking
collagens
Welding
welding
Crosslinking
Closed-loop
feedback control
Feedback control
Laser
Feedback
Lasers
Feedback Control
lasers
surface temperature
Optical fibers
optical fibers
Optical Fiber

Keywords

  • Feedback control
  • Infrared thermometiy
  • Tissue fusion
  • Tissue welding

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Small IV, W., Celliers, P. M., Kopchok, G. E., Reiser, K. M., Heredia, N. J., Maitland, D. J., ... Matthews, D. L. (1997). In-vivo argon laser vascular welding using thermal feedback: Open- and closed-loop patency and collagen crosslinking. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 2970, pp. 252-256) https://doi.org/10.1117/12.275050

In-vivo argon laser vascular welding using thermal feedback : Open- and closed-loop patency and collagen crosslinking. / Small IV, Ward; Celliers, Peter M.; Kopchok, George E.; Reiser, Karen M.; Heredia, Nicholas J.; Maitland, Duncan J.; Eder, David C.; London, Richard A.; Heilbron, Mauricio; Hussain, Farabi; White, Rodney A.; Da Silva, Luiz B.; Matthews, Dennis L.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 2970 1997. p. 252-256.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Small IV, W, Celliers, PM, Kopchok, GE, Reiser, KM, Heredia, NJ, Maitland, DJ, Eder, DC, London, RA, Heilbron, M, Hussain, F, White, RA, Da Silva, LB & Matthews, DL 1997, In-vivo argon laser vascular welding using thermal feedback: Open- and closed-loop patency and collagen crosslinking. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 2970, pp. 252-256, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII, San Jose, CA, United States, 2/8/97. https://doi.org/10.1117/12.275050
Small IV W, Celliers PM, Kopchok GE, Reiser KM, Heredia NJ, Maitland DJ et al. In-vivo argon laser vascular welding using thermal feedback: Open- and closed-loop patency and collagen crosslinking. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 2970. 1997. p. 252-256 https://doi.org/10.1117/12.275050
Small IV, Ward ; Celliers, Peter M. ; Kopchok, George E. ; Reiser, Karen M. ; Heredia, Nicholas J. ; Maitland, Duncan J. ; Eder, David C. ; London, Richard A. ; Heilbron, Mauricio ; Hussain, Farabi ; White, Rodney A. ; Da Silva, Luiz B. ; Matthews, Dennis L. / In-vivo argon laser vascular welding using thermal feedback : Open- and closed-loop patency and collagen crosslinking. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 2970 1997. pp. 252-256
@inproceedings{f31cd385edad46d7ae5c696c2e4aac14,
title = "In-vivo argon laser vascular welding using thermal feedback: Open- and closed-loop patency and collagen crosslinking",
abstract = "An in vivo study of vascular welding with a fiber-delivered argon laser was conducted using a canine model. Longitudinal arteriotomies and venotomies were treated on femoral vein and artery. Laser energy was delivered to the vessel wall via a 400 micrometer optical fiber. The surface temperature at the center of the laser spot was monitored in real time using a hollow glass optical fiber-based two-color infrared thermometer. The surface temperature was limited by either a room-temperature saline drip or direct feedback control of the laser using a mechanical shutter to alternately pass and block the laser. Acute patency was evaluated either visually (leak/no leak) or by in vivo burst pressure measurements. Biochemical assays were performed to investigate the possible laser-induced formation or destruction of enzymatically mediated covalent crosslinks between collagen molecules. Viable welds were created both with and without the use of feedback control. Tissues maintained at 50 degrees Celsius using feedback control had an elevated crosslink count compared to controls, while those irradiated without feedback control experienced a decrease. Differences between the volumetric heating associated with open and closed loop protocols may account for the different effects on collagen crosslinks. Covalent mechanisms may play a role in argon laser vascular fusion.",
keywords = "Feedback control, Infrared thermometiy, Tissue fusion, Tissue welding",
author = "{Small IV}, Ward and Celliers, {Peter M.} and Kopchok, {George E.} and Reiser, {Karen M.} and Heredia, {Nicholas J.} and Maitland, {Duncan J.} and Eder, {David C.} and London, {Richard A.} and Mauricio Heilbron and Farabi Hussain and White, {Rodney A.} and {Da Silva}, {Luiz B.} and Matthews, {Dennis L}",
year = "1997",
doi = "10.1117/12.275050",
language = "English (US)",
volume = "2970",
pages = "252--256",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

}

TY - GEN

T1 - In-vivo argon laser vascular welding using thermal feedback

T2 - Open- and closed-loop patency and collagen crosslinking

AU - Small IV, Ward

AU - Celliers, Peter M.

AU - Kopchok, George E.

AU - Reiser, Karen M.

AU - Heredia, Nicholas J.

AU - Maitland, Duncan J.

AU - Eder, David C.

AU - London, Richard A.

AU - Heilbron, Mauricio

AU - Hussain, Farabi

AU - White, Rodney A.

AU - Da Silva, Luiz B.

AU - Matthews, Dennis L

PY - 1997

Y1 - 1997

N2 - An in vivo study of vascular welding with a fiber-delivered argon laser was conducted using a canine model. Longitudinal arteriotomies and venotomies were treated on femoral vein and artery. Laser energy was delivered to the vessel wall via a 400 micrometer optical fiber. The surface temperature at the center of the laser spot was monitored in real time using a hollow glass optical fiber-based two-color infrared thermometer. The surface temperature was limited by either a room-temperature saline drip or direct feedback control of the laser using a mechanical shutter to alternately pass and block the laser. Acute patency was evaluated either visually (leak/no leak) or by in vivo burst pressure measurements. Biochemical assays were performed to investigate the possible laser-induced formation or destruction of enzymatically mediated covalent crosslinks between collagen molecules. Viable welds were created both with and without the use of feedback control. Tissues maintained at 50 degrees Celsius using feedback control had an elevated crosslink count compared to controls, while those irradiated without feedback control experienced a decrease. Differences between the volumetric heating associated with open and closed loop protocols may account for the different effects on collagen crosslinks. Covalent mechanisms may play a role in argon laser vascular fusion.

AB - An in vivo study of vascular welding with a fiber-delivered argon laser was conducted using a canine model. Longitudinal arteriotomies and venotomies were treated on femoral vein and artery. Laser energy was delivered to the vessel wall via a 400 micrometer optical fiber. The surface temperature at the center of the laser spot was monitored in real time using a hollow glass optical fiber-based two-color infrared thermometer. The surface temperature was limited by either a room-temperature saline drip or direct feedback control of the laser using a mechanical shutter to alternately pass and block the laser. Acute patency was evaluated either visually (leak/no leak) or by in vivo burst pressure measurements. Biochemical assays were performed to investigate the possible laser-induced formation or destruction of enzymatically mediated covalent crosslinks between collagen molecules. Viable welds were created both with and without the use of feedback control. Tissues maintained at 50 degrees Celsius using feedback control had an elevated crosslink count compared to controls, while those irradiated without feedback control experienced a decrease. Differences between the volumetric heating associated with open and closed loop protocols may account for the different effects on collagen crosslinks. Covalent mechanisms may play a role in argon laser vascular fusion.

KW - Feedback control

KW - Infrared thermometiy

KW - Tissue fusion

KW - Tissue welding

UR - http://www.scopus.com/inward/record.url?scp=0005465665&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0005465665&partnerID=8YFLogxK

U2 - 10.1117/12.275050

DO - 10.1117/12.275050

M3 - Conference contribution

VL - 2970

SP - 252

EP - 256

BT - Proceedings of SPIE - The International Society for Optical Engineering

ER -