In vitro fermentation of breast milk oligosaccharides by Bifidobacterium infantis and Lactobacillus gasseri

Robert E. Ward, Milady Niñonuevo, David A. Mills, Carlito B Lebrilla, J. Bruce German

Research output: Contribution to journalArticle

172 Scopus citations


It has been proposed that human milk oligosaccharides (HMO) function as a prebiotic for bifidobacteria, yet this activity has not been adequately investigated. In this study, Bifidobacterium infantis was shown to ferment purified HMO as a sole carbon source, while another gut commensal, Lactobacillus gasseri, did not ferment HMO. Our results support the hypothesis that HMO selectively amplify bacterial populations in the infant intestine.

Original languageEnglish (US)
Pages (from-to)4497-4499
Number of pages3
JournalApplied and Environmental Microbiology
Issue number6
StatePublished - Jun 2006


ASJC Scopus subject areas

  • Environmental Science(all)
  • Biotechnology
  • Microbiology

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