In vitro adherence of Lactobacillus species to vaginal epithelial cells

Janice R. Wood; Richard L Sweet; Anthony Catena; W. Keith Hadley; Marilyn Robbie

doi:10.1016/0002-9378(85)90336-9

In vitro adherence of Lactobacillus species to vaginal epithelial cells

Janice R. Wood, Richard L Sweet, Anthony Catena, W. Keith Hadley, Marilyn Robbie

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Because of the reported useof yogurt douches for the treatment of vaginitis, the adherence of Lactobacillus species to normal human vaginal epithelial cells was tested by in vitro methods. L. acidophilus and L. bulgaricus isolated from three commercial yogurts were compared to L. acidophilus, L. fermentum, L. cellobiosus, and L. casei isolated from clinical specimens and from American Type Culture Collection cultures. L. acidophilus isolated from Lactinex tablets was also tested. No significant difference was found among the 19 clinical isolates, the American Type Culture Collection cultures, and the Lactinex isolate, but all showed significantly higher (p < 0.01) adherence than any Lactobacillus isolated from yogurt. The presence of Gardnerella vaginalis, which adheres strongly to vaginal epithelial cells, was found to interfere with the adherence of lactobacilli from all sources studied.

Original language	English (US)
Pages (from-to)	740-743
Number of pages	4
Journal	American Journal of Obstetrics and Gynecology
Volume	153
Issue number	7
DOIs	https://doi.org/10.1016/0002-9378(85)90336-9
State	Published - Dec 1 1985

Keywords

Adherence
Lactobacillus
vaginitis

ASJC Scopus subject areas

Medicine(all)
Obstetrics and Gynecology

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10.1016/0002-9378(85)90336-9

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title = "In vitro adherence of Lactobacillus species to vaginal epithelial cells",

abstract = "Because of the reported useof yogurt douches for the treatment of vaginitis, the adherence of Lactobacillus species to normal human vaginal epithelial cells was tested by in vitro methods. L. acidophilus and L. bulgaricus isolated from three commercial yogurts were compared to L. acidophilus, L. fermentum, L. cellobiosus, and L. casei isolated from clinical specimens and from American Type Culture Collection cultures. L. acidophilus isolated from Lactinex tablets was also tested. No significant difference was found among the 19 clinical isolates, the American Type Culture Collection cultures, and the Lactinex isolate, but all showed significantly higher (p < 0.01) adherence than any Lactobacillus isolated from yogurt. The presence of Gardnerella vaginalis, which adheres strongly to vaginal epithelial cells, was found to interfere with the adherence of lactobacilli from all sources studied.",

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AU - Wood, Janice R.

AU - Sweet, Richard L

AU - Catena, Anthony

AU - Hadley, W. Keith

AU - Robbie, Marilyn

PY - 1985/12/1

Y1 - 1985/12/1

N2 - Because of the reported useof yogurt douches for the treatment of vaginitis, the adherence of Lactobacillus species to normal human vaginal epithelial cells was tested by in vitro methods. L. acidophilus and L. bulgaricus isolated from three commercial yogurts were compared to L. acidophilus, L. fermentum, L. cellobiosus, and L. casei isolated from clinical specimens and from American Type Culture Collection cultures. L. acidophilus isolated from Lactinex tablets was also tested. No significant difference was found among the 19 clinical isolates, the American Type Culture Collection cultures, and the Lactinex isolate, but all showed significantly higher (p < 0.01) adherence than any Lactobacillus isolated from yogurt. The presence of Gardnerella vaginalis, which adheres strongly to vaginal epithelial cells, was found to interfere with the adherence of lactobacilli from all sources studied.

AB - Because of the reported useof yogurt douches for the treatment of vaginitis, the adherence of Lactobacillus species to normal human vaginal epithelial cells was tested by in vitro methods. L. acidophilus and L. bulgaricus isolated from three commercial yogurts were compared to L. acidophilus, L. fermentum, L. cellobiosus, and L. casei isolated from clinical specimens and from American Type Culture Collection cultures. L. acidophilus isolated from Lactinex tablets was also tested. No significant difference was found among the 19 clinical isolates, the American Type Culture Collection cultures, and the Lactinex isolate, but all showed significantly higher (p < 0.01) adherence than any Lactobacillus isolated from yogurt. The presence of Gardnerella vaginalis, which adheres strongly to vaginal epithelial cells, was found to interfere with the adherence of lactobacilli from all sources studied.

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KW - Lactobacillus

KW - vaginitis

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ER -

In vitro adherence of Lactobacillus species to vaginal epithelial cells

Abstract

Keywords

ASJC Scopus subject areas

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