Improving the spatial resolution characteristics of dedicated cone-beam breast CT technology

Peymon Gazi; John M Boone

doi:10.1117/12.2043243

Improving the spatial resolution characteristics of dedicated cone-beam breast CT technology

Peymon Gazi, John M Boone

Radiology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Scopus citations

Abstract

Prior studies have shown that breast CT (bCT) outperforms mammography in the visualization of mass lesions, yet underperforms in the detection of micro-calcifications. The Breast Tomography Project at UC Davis has successively developed and fabricated four dedicated breast CT scanners, the most recent code-named Doheny, that produce high resolution, fully tomographic images, and overcome the tissue superposition effects of mammography at equivalent radiation dose. Over 600 patients have been imaged thus far in an ongoing clinical trial. The Doheny prototype differs from prior bCT generations in its usage of a pulsed rather than continuous x-ray source and in its utilization of a CMOS flat-panel fluoroscopic detector rather than TFT. Spatial Resolution analysis performed on Doheny indicates that the MTF characteristics have been substantially improved.

Original language	English (US)
Title of host publication	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Publisher	SPIE
Volume	9033
ISBN (Print)	9780819498267
DOIs	https://doi.org/10.1117/12.2043243
State	Published - 2014
Event	Medical Imaging 2014: Physics of Medical Imaging - San Diego, CA, United States Duration: Feb 17 2014 → Feb 20 2014

Other

Other	Medical Imaging 2014: Physics of Medical Imaging
Country	United States
City	San Diego, CA
Period	2/17/14 → 2/20/14

Keywords

Computed Tomography
Cone-beam CT
Dedicated breast CT
mammography
X-ray radiation

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Biomaterials
Radiology Nuclear Medicine and imaging

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10.1117/12.2043243

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Cite this

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title = "Improving the spatial resolution characteristics of dedicated cone-beam breast CT technology",

abstract = "Prior studies have shown that breast CT (bCT) outperforms mammography in the visualization of mass lesions, yet underperforms in the detection of micro-calcifications. The Breast Tomography Project at UC Davis has successively developed and fabricated four dedicated breast CT scanners, the most recent code-named Doheny, that produce high resolution, fully tomographic images, and overcome the tissue superposition effects of mammography at equivalent radiation dose. Over 600 patients have been imaged thus far in an ongoing clinical trial. The Doheny prototype differs from prior bCT generations in its usage of a pulsed rather than continuous x-ray source and in its utilization of a CMOS flat-panel fluoroscopic detector rather than TFT. Spatial Resolution analysis performed on Doheny indicates that the MTF characteristics have been substantially improved.",

keywords = "Computed Tomography, Cone-beam CT, Dedicated breast CT, mammography, X-ray radiation",

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AU - Boone, John M

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AB - Prior studies have shown that breast CT (bCT) outperforms mammography in the visualization of mass lesions, yet underperforms in the detection of micro-calcifications. The Breast Tomography Project at UC Davis has successively developed and fabricated four dedicated breast CT scanners, the most recent code-named Doheny, that produce high resolution, fully tomographic images, and overcome the tissue superposition effects of mammography at equivalent radiation dose. Over 600 patients have been imaged thus far in an ongoing clinical trial. The Doheny prototype differs from prior bCT generations in its usage of a pulsed rather than continuous x-ray source and in its utilization of a CMOS flat-panel fluoroscopic detector rather than TFT. Spatial Resolution analysis performed on Doheny indicates that the MTF characteristics have been substantially improved.

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KW - mammography

KW - X-ray radiation

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