Improving the spatial resolution characteristics of dedicated cone-beam breast CT technology

Peymon Gazi, John M Boone

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations


Prior studies have shown that breast CT (bCT) outperforms mammography in the visualization of mass lesions, yet underperforms in the detection of micro-calcifications. The Breast Tomography Project at UC Davis has successively developed and fabricated four dedicated breast CT scanners, the most recent code-named Doheny, that produce high resolution, fully tomographic images, and overcome the tissue superposition effects of mammography at equivalent radiation dose. Over 600 patients have been imaged thus far in an ongoing clinical trial. The Doheny prototype differs from prior bCT generations in its usage of a pulsed rather than continuous x-ray source and in its utilization of a CMOS flat-panel fluoroscopic detector rather than TFT. Spatial Resolution analysis performed on Doheny indicates that the MTF characteristics have been substantially improved.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISBN (Print)9780819498267
StatePublished - 2014
EventMedical Imaging 2014: Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 17 2014Feb 20 2014


OtherMedical Imaging 2014: Physics of Medical Imaging
Country/TerritoryUnited States
CitySan Diego, CA


  • Computed Tomography
  • Cone-beam CT
  • Dedicated breast CT
  • mammography
  • X-ray radiation

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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