Improving nanoprobes using surface-enhanced Raman scattering from 30-nm hollow gold particles

Adam M. Schwartzberg, Tammy Y. Oshiro, Jin Z. Zhang, Thomas R Huser, Chad E. Talley

Research output: Contribution to journalArticle

169 Citations (Scopus)

Abstract

We report the development of nanoprobes that exploit the surface-enhanced Raman scattering (SERS) from nonaggregated, hollow, gold nanospheres (HGNSs). The homogeneity of the HGNSs leads to a nearly 10-fold improvement in signal consistency over standard silver SERS substrates, which translates into a significant increase in sensitivity and dynamic range for the model application of pH sensing. Moreover, the small size (30-nm diameter) of these SERS-active nanoparticles represents a major step in advancing sensing technology based on SERS, making this technology more amenable to intracellular sensing.

Original languageEnglish (US)
Pages (from-to)4732-4736
Number of pages5
JournalAnalytical Chemistry
Volume78
Issue number13
DOIs
StatePublished - Jul 1 2006

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Nanoprobes
Gold
Raman scattering
Nanospheres
Silver
Nanoparticles
Substrates

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Schwartzberg, A. M., Oshiro, T. Y., Zhang, J. Z., Huser, T. R., & Talley, C. E. (2006). Improving nanoprobes using surface-enhanced Raman scattering from 30-nm hollow gold particles. Analytical Chemistry, 78(13), 4732-4736. https://doi.org/10.1021/ac060220g

Improving nanoprobes using surface-enhanced Raman scattering from 30-nm hollow gold particles. / Schwartzberg, Adam M.; Oshiro, Tammy Y.; Zhang, Jin Z.; Huser, Thomas R; Talley, Chad E.

In: Analytical Chemistry, Vol. 78, No. 13, 01.07.2006, p. 4732-4736.

Research output: Contribution to journalArticle

Schwartzberg, AM, Oshiro, TY, Zhang, JZ, Huser, TR & Talley, CE 2006, 'Improving nanoprobes using surface-enhanced Raman scattering from 30-nm hollow gold particles', Analytical Chemistry, vol. 78, no. 13, pp. 4732-4736. https://doi.org/10.1021/ac060220g
Schwartzberg, Adam M. ; Oshiro, Tammy Y. ; Zhang, Jin Z. ; Huser, Thomas R ; Talley, Chad E. / Improving nanoprobes using surface-enhanced Raman scattering from 30-nm hollow gold particles. In: Analytical Chemistry. 2006 ; Vol. 78, No. 13. pp. 4732-4736.
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