Abstract
We demonstrate the feasibility of our newly developed phase stabilized high-speed (100 kHz A-scans/s) 1 μm sweptsource optical coherence tomography (SSOCT) system with the phase-variance based motion contrast method for visualization of human chorioretinal complex microcirculation. Compared to our previously reported spectral domain (spectrometer based) phase-variance (pv)-SDOCT system it has advantages of higher sensitivity, reduced fringe washout for high blood flow speeds and deeper penetration in choroid. High phase stability SSOCT imaging was achieved by using a computationally efficient phase stabilization approach. This process does not require additional calibration hardware and complex numerical procedures. Our phase stabilization method is simple and can be employed in a variety of SS-OCT systems. Examples of vasculature in the chorioretinal complex imaged by pv-SSOCT is presented and compared to retinal images of the same volunteers acquired with fluorescein angiography (FA) and indocyanine green angiography (ICGA).
Original language | English (US) |
---|---|
Title of host publication | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
Publisher | SPIE |
Volume | 8930 |
ISBN (Print) | 9780819498434 |
DOIs | |
State | Published - 2014 |
Event | 24th Conference on Ophthalmic Technologies - San Francisco, CA, United States Duration: Feb 1 2014 → Feb 2 2014 |
Other
Other | 24th Conference on Ophthalmic Technologies |
---|---|
Country | United States |
City | San Francisco, CA |
Period | 2/1/14 → 2/2/14 |
Keywords
- Medical and biological imaging
- Medical optics instrumentation
- Ophthalmic optics and devices
- Ophthalmology
- Optical coherence tomography
- Retinal blood flow
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging