Importance of follow-up medical and surgical approaches to prevent reinfarction, reocclusion, and recurrent angina following intracoronary thrombolysis with streptokinase in acute myocardial infarction

Garrett Lee, Reginald Low, Patricia Takeda, Priscilla Joe, Anthony N. DeMaria, Ezra A Amsterdam, Henry Lui, Peter Dietrich, Kelvin Lee, Dean T. Mason

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Thirty-four patients with acute myocardial infarction (mean age 55 years) who received intracoronary streptokinase for coronary thrombosis were followed for a mean of 9.4 months (longest 25 months) following the procedure of percutaneous transluminal coronary recanalization (PTCR). Twelve patients had undergone coronary artery bypass graft surgery (CABG), one had percutaneous transluminal coronary angloplasty (PTCA), and 21 recelved medical therapy. Among patients having CABG and PTCA, nearly 70% no longer had chest pain or reinfarction, and 62% were in New York functional class I status; there were no deaths, and there was only one reinfarction, in a patient who had graft closure. In contrast, 43% of medically treated patients had chest pain or reinfarction or had died on follow-up; only 32% of survivors were in class I functional status. Further, 71% of medically treated patients who were receiving warfarin had no chest pain and no reinfarction, whereas the majority (56%) of patients who did not receive either warfarin or antiplatelet agents either had chest pain or reinfarction or died. The importance of CABG PTCA and anticoagulant therapy is stressed to prevent recurrent ischemia, reinfarction, and reocclusion following successful reperfusion by means of PTCR in acute myocardial infarction.

Original languageEnglish (US)
Pages (from-to)921-924
Number of pages4
JournalAmerican Heart Journal
Volume104
Issue number4 PART 2
DOIs
StatePublished - 1982

Fingerprint

Streptokinase
Myocardial Infarction
Chest Pain
Coronary Artery Bypass
Transplants
Warfarin
Coronary Thrombosis
Platelet Aggregation Inhibitors
Anticoagulants
Reperfusion
Survivors
Ischemia
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Importance of follow-up medical and surgical approaches to prevent reinfarction, reocclusion, and recurrent angina following intracoronary thrombolysis with streptokinase in acute myocardial infarction. / Lee, Garrett; Low, Reginald; Takeda, Patricia; Joe, Priscilla; DeMaria, Anthony N.; Amsterdam, Ezra A; Lui, Henry; Dietrich, Peter; Lee, Kelvin; Mason, Dean T.

In: American Heart Journal, Vol. 104, No. 4 PART 2, 1982, p. 921-924.

Research output: Contribution to journalArticle

Lee, Garrett ; Low, Reginald ; Takeda, Patricia ; Joe, Priscilla ; DeMaria, Anthony N. ; Amsterdam, Ezra A ; Lui, Henry ; Dietrich, Peter ; Lee, Kelvin ; Mason, Dean T. / Importance of follow-up medical and surgical approaches to prevent reinfarction, reocclusion, and recurrent angina following intracoronary thrombolysis with streptokinase in acute myocardial infarction. In: American Heart Journal. 1982 ; Vol. 104, No. 4 PART 2. pp. 921-924.
@article{8ca878ac2b9143268c7e947b8193a1de,
title = "Importance of follow-up medical and surgical approaches to prevent reinfarction, reocclusion, and recurrent angina following intracoronary thrombolysis with streptokinase in acute myocardial infarction",
abstract = "Thirty-four patients with acute myocardial infarction (mean age 55 years) who received intracoronary streptokinase for coronary thrombosis were followed for a mean of 9.4 months (longest 25 months) following the procedure of percutaneous transluminal coronary recanalization (PTCR). Twelve patients had undergone coronary artery bypass graft surgery (CABG), one had percutaneous transluminal coronary angloplasty (PTCA), and 21 recelved medical therapy. Among patients having CABG and PTCA, nearly 70{\%} no longer had chest pain or reinfarction, and 62{\%} were in New York functional class I status; there were no deaths, and there was only one reinfarction, in a patient who had graft closure. In contrast, 43{\%} of medically treated patients had chest pain or reinfarction or had died on follow-up; only 32{\%} of survivors were in class I functional status. Further, 71{\%} of medically treated patients who were receiving warfarin had no chest pain and no reinfarction, whereas the majority (56{\%}) of patients who did not receive either warfarin or antiplatelet agents either had chest pain or reinfarction or died. The importance of CABG PTCA and anticoagulant therapy is stressed to prevent recurrent ischemia, reinfarction, and reocclusion following successful reperfusion by means of PTCR in acute myocardial infarction.",
author = "Garrett Lee and Reginald Low and Patricia Takeda and Priscilla Joe and DeMaria, {Anthony N.} and Amsterdam, {Ezra A} and Henry Lui and Peter Dietrich and Kelvin Lee and Mason, {Dean T.}",
year = "1982",
doi = "10.1016/0002-8703(82)90265-4",
language = "English (US)",
volume = "104",
pages = "921--924",
journal = "American Heart Journal",
issn = "0002-8703",
publisher = "Mosby Inc.",
number = "4 PART 2",

}

TY - JOUR

T1 - Importance of follow-up medical and surgical approaches to prevent reinfarction, reocclusion, and recurrent angina following intracoronary thrombolysis with streptokinase in acute myocardial infarction

AU - Lee, Garrett

AU - Low, Reginald

AU - Takeda, Patricia

AU - Joe, Priscilla

AU - DeMaria, Anthony N.

AU - Amsterdam, Ezra A

AU - Lui, Henry

AU - Dietrich, Peter

AU - Lee, Kelvin

AU - Mason, Dean T.

PY - 1982

Y1 - 1982

N2 - Thirty-four patients with acute myocardial infarction (mean age 55 years) who received intracoronary streptokinase for coronary thrombosis were followed for a mean of 9.4 months (longest 25 months) following the procedure of percutaneous transluminal coronary recanalization (PTCR). Twelve patients had undergone coronary artery bypass graft surgery (CABG), one had percutaneous transluminal coronary angloplasty (PTCA), and 21 recelved medical therapy. Among patients having CABG and PTCA, nearly 70% no longer had chest pain or reinfarction, and 62% were in New York functional class I status; there were no deaths, and there was only one reinfarction, in a patient who had graft closure. In contrast, 43% of medically treated patients had chest pain or reinfarction or had died on follow-up; only 32% of survivors were in class I functional status. Further, 71% of medically treated patients who were receiving warfarin had no chest pain and no reinfarction, whereas the majority (56%) of patients who did not receive either warfarin or antiplatelet agents either had chest pain or reinfarction or died. The importance of CABG PTCA and anticoagulant therapy is stressed to prevent recurrent ischemia, reinfarction, and reocclusion following successful reperfusion by means of PTCR in acute myocardial infarction.

AB - Thirty-four patients with acute myocardial infarction (mean age 55 years) who received intracoronary streptokinase for coronary thrombosis were followed for a mean of 9.4 months (longest 25 months) following the procedure of percutaneous transluminal coronary recanalization (PTCR). Twelve patients had undergone coronary artery bypass graft surgery (CABG), one had percutaneous transluminal coronary angloplasty (PTCA), and 21 recelved medical therapy. Among patients having CABG and PTCA, nearly 70% no longer had chest pain or reinfarction, and 62% were in New York functional class I status; there were no deaths, and there was only one reinfarction, in a patient who had graft closure. In contrast, 43% of medically treated patients had chest pain or reinfarction or had died on follow-up; only 32% of survivors were in class I functional status. Further, 71% of medically treated patients who were receiving warfarin had no chest pain and no reinfarction, whereas the majority (56%) of patients who did not receive either warfarin or antiplatelet agents either had chest pain or reinfarction or died. The importance of CABG PTCA and anticoagulant therapy is stressed to prevent recurrent ischemia, reinfarction, and reocclusion following successful reperfusion by means of PTCR in acute myocardial infarction.

UR - http://www.scopus.com/inward/record.url?scp=0020282691&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020282691&partnerID=8YFLogxK

U2 - 10.1016/0002-8703(82)90265-4

DO - 10.1016/0002-8703(82)90265-4

M3 - Article

C2 - 6214940

AN - SCOPUS:0020282691

VL - 104

SP - 921

EP - 924

JO - American Heart Journal

JF - American Heart Journal

SN - 0002-8703

IS - 4 PART 2

ER -