Implication of sialidases in Salmonella infection: Genome release of sialidase knockout strains from salmonella enterica serovar Typhimurium LT2

Narine Arabyan; Allison M. Weis; Bihua C. Huang; Bart C Weimer

doi:10.1128/genomeA.00341-17

Implication of sialidases in Salmonella infection: Genome release of sialidase knockout strains from salmonella enterica serovar Typhimurium LT2

Narine Arabyan, Allison M. Weis, Bihua C. Huang, Bart C Weimer

Population Health and Reproduction

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Abstract

Sialidases, which are widely distributed in nature, cleave the α-ketosidic bond of terminal sialic acid residue. These emerging virulence factors degrade the host glycan. We report here the release of seven sialidase and one sialic acid transporter deletion in Salmonella enterica serovar Typhimurium strain LT2, which are important in cellular invasion during infection.

Original language	English (US)
Article number	e00341-17
Journal	Genome Announcements
Volume	5
Issue number	19
DOIs	https://doi.org/10.1128/genomeA.00341-17
State	Published - 2017

ASJC Scopus subject areas

Genetics
Molecular Biology

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abstract = "Sialidases, which are widely distributed in nature, cleave the α-ketosidic bond of terminal sialic acid residue. These emerging virulence factors degrade the host glycan. We report here the release of seven sialidase and one sialic acid transporter deletion in Salmonella enterica serovar Typhimurium strain LT2, which are important in cellular invasion during infection.",

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AU - Weimer, Bart C

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AB - Sialidases, which are widely distributed in nature, cleave the α-ketosidic bond of terminal sialic acid residue. These emerging virulence factors degrade the host glycan. We report here the release of seven sialidase and one sialic acid transporter deletion in Salmonella enterica serovar Typhimurium strain LT2, which are important in cellular invasion during infection.

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Implication of sialidases in Salmonella infection: Genome release of sialidase knockout strains from salmonella enterica serovar Typhimurium LT2

Abstract

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