Impaired quality of sleep in Ménière's disease patients

Meiho Nakayama, Motohiko Suzuki, Akira Inagaki, Keiji Takemura, Nobuhiro Watanabe, Tohru Tanigawa, Kazushi Okamoto, Hirokazu Hattori, Hilary A Brodie, Shingo Murakami

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Objective: To evaluate the quality of sleep in Ménière's disease patients with the use of polysomnography. Study Design: Prospective study using polysomnography administered in patients diagnosed as "Definite Ménière's disease cases" according to the guidelines of the American Academy of Otolaryngology-Head and Neck Surgery. Methods: Thirty-five patients, 17 male and 18 female, aged 31 to 71 (58 average) years with active, unilateral, cochleovestibular Ménière's disease refractory to medical management underwent polysomnography. The results were compared with 35 healthy controls matched for age and sex. All participants underwent full-night polysomnography, and a sleep medicine physician interpreted the results. Results: Total sleeping time in Ménière's disease was significantly higher than in controls. Stage 2 sleep was significantly longer and stage 3+4 shorter in Ménière's disease than controis, while there was no difference of stage 1 and REM. Arousal index was significantly higher in Ménière's disease than in controls. Five cases of severe OSAS were found in Ménière's disease and 4 cases in controls; 4 cases of PLMD were found in patients and 3 in controls. Conclusions: Our finding of decreased deep sleep and an elevated arousal index is a striking new finding in Ménière's disease. This poor quality of sleep in Ménière's disease patients has received little attention in the past, but may cause additional stress and lead to a negative spiral of symptoms.

Original languageEnglish (US)
Pages (from-to)445-449
Number of pages5
JournalJournal of Clinical Sleep Medicine
Volume6
Issue number5
StatePublished - Oct 15 2010

Fingerprint

Sleep
Polysomnography
Arousal
Sleep Stages
Otolaryngology
Neck
Head
Medicine
Prospective Studies
Guidelines
Physicians

Keywords

  • Ménière's disease
  • OSAS
  • PLMD
  • Polysomnography
  • Sleep
  • Stress

ASJC Scopus subject areas

  • Clinical Neurology
  • Pulmonary and Respiratory Medicine
  • Neurology

Cite this

Nakayama, M., Suzuki, M., Inagaki, A., Takemura, K., Watanabe, N., Tanigawa, T., ... Murakami, S. (2010). Impaired quality of sleep in Ménière's disease patients. Journal of Clinical Sleep Medicine, 6(5), 445-449.

Impaired quality of sleep in Ménière's disease patients. / Nakayama, Meiho; Suzuki, Motohiko; Inagaki, Akira; Takemura, Keiji; Watanabe, Nobuhiro; Tanigawa, Tohru; Okamoto, Kazushi; Hattori, Hirokazu; Brodie, Hilary A; Murakami, Shingo.

In: Journal of Clinical Sleep Medicine, Vol. 6, No. 5, 15.10.2010, p. 445-449.

Research output: Contribution to journalArticle

Nakayama, M, Suzuki, M, Inagaki, A, Takemura, K, Watanabe, N, Tanigawa, T, Okamoto, K, Hattori, H, Brodie, HA & Murakami, S 2010, 'Impaired quality of sleep in Ménière's disease patients', Journal of Clinical Sleep Medicine, vol. 6, no. 5, pp. 445-449.
Nakayama M, Suzuki M, Inagaki A, Takemura K, Watanabe N, Tanigawa T et al. Impaired quality of sleep in Ménière's disease patients. Journal of Clinical Sleep Medicine. 2010 Oct 15;6(5):445-449.
Nakayama, Meiho ; Suzuki, Motohiko ; Inagaki, Akira ; Takemura, Keiji ; Watanabe, Nobuhiro ; Tanigawa, Tohru ; Okamoto, Kazushi ; Hattori, Hirokazu ; Brodie, Hilary A ; Murakami, Shingo. / Impaired quality of sleep in Ménière's disease patients. In: Journal of Clinical Sleep Medicine. 2010 ; Vol. 6, No. 5. pp. 445-449.
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