Impaired acquisition and rapid forgetting of patterned visual stimuli in Alzheimer's disease

Bruce R Reed, Ken A. Paller, Dan M Mungas

Research output: Contribution to journalArticle

15 Scopus citations


Whether or not rate of forgetting is accelerated in Alzheimer's disease (AD) is controversial. This study examined recognition of visual patterns in patients with AD and in controls at 10 min relative to a learning baseline measured after a 10-s delay (delayed recognition ratio, DRR). Comparable baseline performances were attained in the two groups by manipulating stimulus exposure times. Comparisons between 25 AD and 48 age-matched controls demonstrated lower DRR in AD when initial recognition, which was statistically worse in AD, was covariated. DRR was also lower in an analysis of subgroups closely matched on initial performance. The findings suggest that forgetting is accelerated in AD because multiple aspects of memory processing, including storage, are impaired.

Original languageEnglish (US)
Pages (from-to)738-749
Number of pages12
JournalJournal of Clinical and Experimental Neuropsychology
Issue number5
StatePublished - 1998


ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Psychology(all)
  • Clinical Psychology

Cite this