Impact of reinduction regimens on the clinical course of adult acute nonlymphocytic leukemia

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15 Scopus citations

Abstract

All clinical studies in the English literature from 1976 to mid-1987 that address drug management of refractory or relapsed ANLL are reviewed and summarized. We conclude that, although many regimens may induce a CR, none is clearly superior. New drugs and or drug combinations must be sought if treatment outcomes are to be substantially improved. At present it appears that combination chemotherapy with VP-16 has not been extensively studied and may be active in non-cross-resistant regimens.

Original languageEnglish (US)
Pages (from-to)711-716
Number of pages6
JournalLeukemia
Volume2
Issue number11
StatePublished - 1988

ASJC Scopus subject areas

  • Cancer Research
  • Hematology

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