Impact of Gender and Age on In Vivo Virtual Histology-Intravascular Ultrasound Imaging Plaque Characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] Registry)

Jie Qian, Akiko Maehara, Gary S. Mintz, M. Pauliina Margolis, Amir Lerman, Jason H Rogers, Shuel Banai, Samer Kazziha, Celia Castellanos, Lokesh Dani, Martin Fahy, Gregg W. Stone, Martin B. Leon

Research output: Contribution to journalArticle

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Abstract

Virtual histology intravascular ultrasound (VH-IVUS) analyses were performed in the first 990 patients enrolled in the 3,000+ patient global VH-IVUS Registry to assess the impact of gender and age on in vivo VH-IVUS plaque characterization. The 990 patients were divided into 3 age group terciles (<58, 58 to 68, and >68 years) and again divided according to gender. In conclusion, (1) both women and men had an increase in plaque with increasing age; (2) at any age, men had more plaque than women; (3) percentages of dense calcium and necrotic core increased with increasing patient age in both men and women; and (4) gender differences were lowest in the oldest tercile (>68 years).

Original languageEnglish (US)
Pages (from-to)1210-1214
Number of pages5
JournalAmerican Journal of Cardiology
Volume103
Issue number9
DOIs
StatePublished - May 1 2009

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Registries
Ultrasonography
Histology
Age Groups
Calcium

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Impact of Gender and Age on In Vivo Virtual Histology-Intravascular Ultrasound Imaging Plaque Characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] Registry). / Qian, Jie; Maehara, Akiko; Mintz, Gary S.; Margolis, M. Pauliina; Lerman, Amir; Rogers, Jason H; Banai, Shuel; Kazziha, Samer; Castellanos, Celia; Dani, Lokesh; Fahy, Martin; Stone, Gregg W.; Leon, Martin B.

In: American Journal of Cardiology, Vol. 103, No. 9, 01.05.2009, p. 1210-1214.

Research output: Contribution to journalArticle

Qian, Jie ; Maehara, Akiko ; Mintz, Gary S. ; Margolis, M. Pauliina ; Lerman, Amir ; Rogers, Jason H ; Banai, Shuel ; Kazziha, Samer ; Castellanos, Celia ; Dani, Lokesh ; Fahy, Martin ; Stone, Gregg W. ; Leon, Martin B. / Impact of Gender and Age on In Vivo Virtual Histology-Intravascular Ultrasound Imaging Plaque Characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] Registry). In: American Journal of Cardiology. 2009 ; Vol. 103, No. 9. pp. 1210-1214.
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abstract = "Virtual histology intravascular ultrasound (VH-IVUS) analyses were performed in the first 990 patients enrolled in the 3,000+ patient global VH-IVUS Registry to assess the impact of gender and age on in vivo VH-IVUS plaque characterization. The 990 patients were divided into 3 age group terciles (<58, 58 to 68, and >68 years) and again divided according to gender. In conclusion, (1) both women and men had an increase in plaque with increasing age; (2) at any age, men had more plaque than women; (3) percentages of dense calcium and necrotic core increased with increasing patient age in both men and women; and (4) gender differences were lowest in the oldest tercile (>68 years).",
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AU - Maehara, Akiko

AU - Mintz, Gary S.

AU - Margolis, M. Pauliina

AU - Lerman, Amir

AU - Rogers, Jason H

AU - Banai, Shuel

AU - Kazziha, Samer

AU - Castellanos, Celia

AU - Dani, Lokesh

AU - Fahy, Martin

AU - Stone, Gregg W.

AU - Leon, Martin B.

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