Abstract
Combined immunodeficiency (CID) in Arabian foals appears to be similar to CID in children. The disease is characterized by a deficiency of T and B lymphocytes. Immunotherapy was attempted in 2 Arabian foals with combined immunodeficiency. One foal was given a transplant of bone marrow from a selected full sibling, and 1 foal was given a fetal thymus transplant. Both foals died. Genetic evidence was obtained for survival of the transplanted tissues in both cases; however, a graft versus host reaction developed in the foal given the fetal thymus transplant.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 167-175 |
| Number of pages | 9 |
| Journal | Journal of the American Veterinary Medical Association |
| Volume | 170 |
| Issue number | 2 |
| State | Published - Oct 3 1977 |
ASJC Scopus subject areas
- veterinary(all)
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Ardans, A., Trommershausen-Smith, A., Osburn, B., Mayhew, I. G., Trees, C., Park, M. I., Sawyer, M., & Stabenfeldt, G. H. (1977). Immunotherapy in two foals with combined immunodeficiency, resulting in graft versus host reaction. Journal of the American Veterinary Medical Association, 170(2), 167-175.