Immunoreactive somatostatin and luteinizing hormone releasing hormone in median eminence synaptosomes of the rat: Detection by immunohistochemistry and quantification by radioimmunoassay

Dennis M Styne, P. C. Goldsmith, S. R. Burstein, S. L. Kaplan, M. M. Grumbach

Research output: Contribution to journalArticle

29 Scopus citations


Somatostatin and LHRH were detected by radioimmunoassay in the synaptosome fraction obtained by homogenization and differential centrifugation of the rat median eminence. Both somatostatin and LHRH were demonstrated by electron microscopic immunocytochemistry in secretory granules within synaptosomes.

Original languageEnglish (US)
Pages (from-to)1099-1103
Number of pages5
Issue number4
StatePublished - 1977
Externally publishedYes


ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this