Immunophysiological responses of horses to a 12-hour rest during 24 hours of road transport

Carolyn Stull, J. Morrow, B. A. Aldridge, Jeffrey L Stott, J. J. McGlone

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Thirty-eight mature horses were assigned to one of two equal groups to evaluate two treatments consisting of either 24 hours of continuous road transport (24T) or two 12-hour periods of transport separated by off-loading, resting and feeding the horses for 12 hours (12/12T). A subset of six horses from each group served as controls for the other group. The horses were loaded into a commercial straight-deck trailer and travelled loose in one of two standard-sized compartments. After the journeys the horses were put back into their paddocks for a 24-hour recovery period. Venous blood samples were collected before loading, after unloading and after the 24-hour recovery period. Transport significantly increased the horses' cortisol concentrations, neutrophil counts and neutrophil:lymphocyte (NL) ratios, and decreased the numbers of all the lymphocyte subpopulation cell types. Collectively, no significant differences were observed between the two treatments in the horses' cortisol concentrations, total leucocyte counts, neutrophil and lymphocyte counts, NL ratios, and the CD8a+ and CD21+ lymphocyte subpopulations, but there were differences in the numbers of CD3+, CD4+, and CD8b+ subpopulations. The inclusion of a 12-hour rest-stop interrupted the transport-related decline in the lymphocyte subpopulations and allowed them to recover towards their resting levels.

Original languageEnglish (US)
Pages (from-to)609-614
Number of pages6
JournalVeterinary Record
Volume162
Issue number19
StatePublished - May 10 2008

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Horses
roads
horses
lymphocytes
neutrophils
Lymphocyte Subsets
Neutrophils
Lymphocyte Count
cortisol
Hydrocortisone
trailers
lymphocyte count
Leukocyte Count
leukocyte count
pastures
Lymphocytes
Control Groups
blood
cells
sampling

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Immunophysiological responses of horses to a 12-hour rest during 24 hours of road transport. / Stull, Carolyn; Morrow, J.; Aldridge, B. A.; Stott, Jeffrey L; McGlone, J. J.

In: Veterinary Record, Vol. 162, No. 19, 10.05.2008, p. 609-614.

Research output: Contribution to journalArticle

Stull, Carolyn ; Morrow, J. ; Aldridge, B. A. ; Stott, Jeffrey L ; McGlone, J. J. / Immunophysiological responses of horses to a 12-hour rest during 24 hours of road transport. In: Veterinary Record. 2008 ; Vol. 162, No. 19. pp. 609-614.
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