Immunopathologic effects of silicone breast implants

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Silicone-gel breast implants have been associated with a myriad of autoimmune and connective tissue disorders by anecdotal reports and small observational series. To date, no prospective epidemiologic studies have been done to substantiate these observations, but an increasing body of literature is being developed and older studies are being recognized that point to immunotoxic or inflammatory effects of these breast implant components. The development of disease due to implants would depend on the interaction of genetic host factors so that only a few patients would potentially be at risk. Based on the example of other chemically mediated disorders, such as scleroderma in association with silica exposure, latency periods of more than 30 years before disease develops may be possible. Herein we review studies on silicone and immunity.

Original languageEnglish (US)
Pages (from-to)418-425
Number of pages8
JournalWestern Journal of Medicine
Volume162
Issue number5
StatePublished - 1995

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Breast Implants
Silicones
Silicone Gels
Silicon Dioxide
Connective Tissue
Epidemiologic Studies
Immunity
Prospective Studies

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Immunopathologic effects of silicone breast implants. / Teuber, Suzanne S; Yoshida, S. H.; Gershwin, M. Eric.

In: Western Journal of Medicine, Vol. 162, No. 5, 1995, p. 418-425.

Research output: Contribution to journalArticle

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