Immunometabolism modulation, a new trick of edible and medicinal plants in cancer treatment

Wen Tan, Tingrui Pan, Shengpeng Wang, Peng Li, Yongfan Men, Rui Tan, Zhangfeng Zhong, Yitao Wang

Research output: Contribution to journalReview articlepeer-review


The edible and medicinal plants (EMPs) are becoming an abundant source for cancer prevention and treatment since the natural and healthy trend for modern human beings. Currently, there are more than one hundred species of EMPs widely used and listed by the national health commission of China, and most of them indicate immune or metabolic regulation potential in cancer treatment with numerous studies over the past two decades. In the present review, we focused on the metabolic influence in immunocytes and tumor microenvironment, including immune response, immunosuppressive factors and cancer cells, discussing the immunometabolic potential of EMPs in cancer treatment. There are more than five hundred references collected and analyzed through retrieving pharmacological studies deposited in PubMed by medical subject headings and the corresponding names derived from pharmacopoeia of China as a sole criterion. Finally, the immunometabolism modulation of EMPs was sketch out implying an immunometabolic control in cancer treatment.

Original languageEnglish (US)
Article number131860
JournalFood Chemistry
StatePublished - May 15 2022
Externally publishedYes


  • Cancer
  • Edible and medicinal plants
  • Immunometabolism
  • Traditional Chinese medicinal herb

ASJC Scopus subject areas

  • Analytical Chemistry
  • Food Science


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