Immunologic surface markers on nonhuman primate lymphocytes.

T. G. Terrell, C. A. Holmberg, Bennie Osburn

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Peripheral blood lymphocytes from 37 healthy rhesus macaques (Macaca mulatta) and thymocytes from 10 fetal and neonatal rhesus macaques were studied for membrane characteristics. Spontaneous rosette formation with sheep erythrocytes, a characteristic of human T lymphocytes, was evaluated. The presence of membrane-bound immunoglobulin and surface receptors for fixed complement was measured, using fluorescent antibody techniques and erythrocyte-antibody-complement rosettes, respectively. The mean percentages +/- 1 standard error of the lymphocyte markers in the peripheral blood lymphocytes from the macaques were: spontaneous rosettes, 63 +/- 1.0; erythrocyte-antibody-complement rosettes, 14.9 +/- 1.2; and membrane immunoglobulin-positive cells, 21.9 +/- 2.2. These values are very similar to values reported for human beings.

Original languageEnglish (US)
Pages (from-to)503-507
Number of pages5
JournalAmerican Journal of Veterinary Research
Volume38
Issue number4
StatePublished - Apr 1 1977
Externally publishedYes

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Surface Antigens
Macaca mulatta
Primates
complement
erythrocytes
lymphocytes
Erythrocytes
Lymphocytes
immunoglobulins
Rosette Formation
Complement Receptors
B-Cell Antigen Receptors
antibodies
thymocytes
Membranes
Antibodies
blood
Macaca
Thymocytes
fluorescent antibody technique

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Terrell, T. G., Holmberg, C. A., & Osburn, B. (1977). Immunologic surface markers on nonhuman primate lymphocytes. American Journal of Veterinary Research, 38(4), 503-507.

Immunologic surface markers on nonhuman primate lymphocytes. / Terrell, T. G.; Holmberg, C. A.; Osburn, Bennie.

In: American Journal of Veterinary Research, Vol. 38, No. 4, 01.04.1977, p. 503-507.

Research output: Contribution to journalArticle

Terrell, TG, Holmberg, CA & Osburn, B 1977, 'Immunologic surface markers on nonhuman primate lymphocytes.', American Journal of Veterinary Research, vol. 38, no. 4, pp. 503-507.
Terrell, T. G. ; Holmberg, C. A. ; Osburn, Bennie. / Immunologic surface markers on nonhuman primate lymphocytes. In: American Journal of Veterinary Research. 1977 ; Vol. 38, No. 4. pp. 503-507.
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