Abstract
Peripheral blood lymphocytes from 37 healthy rhesus macaques (Macaca mulatta) and thymocytes from 10 fetal and neonatal rhesus macaques were studied for membrane characteristics. Spontaneous rosette formation with sheep erythrocytes, a characteristic of human T lymphocytes, was evaluated. The presence of membrane-bound immunoglobulin and surface receptors for fixed complement was measured, using fluorescent antibody techniques and erythrocyte-antibody-complement rosettes, respectively. The mean percentages +/- 1 standard error of the lymphocyte markers in the peripheral blood lymphocytes from the macaques were: spontaneous rosettes, 63 +/- 1.0; erythrocyte-antibody-complement rosettes, 14.9 +/- 1.2; and membrane immunoglobulin-positive cells, 21.9 +/- 2.2. These values are very similar to values reported for human beings.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 503-507 |
| Number of pages | 5 |
| Journal | American Journal of Veterinary Research |
| Volume | 38 |
| Issue number | 4 |
| State | Published - Apr 1 1977 |
| Externally published | Yes |
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Cite this
Immunologic surface markers on nonhuman primate lymphocytes. / Terrell, T. G.; Holmberg, C. A.; Osburn, Bennie.
In: American Journal of Veterinary Research, Vol. 38, No. 4, 01.04.1977, p. 503-507.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Immunologic surface markers on nonhuman primate lymphocytes.
AU - Terrell, T. G.
AU - Holmberg, C. A.
AU - Osburn, Bennie
PY - 1977/4/1
Y1 - 1977/4/1
N2 - Peripheral blood lymphocytes from 37 healthy rhesus macaques (Macaca mulatta) and thymocytes from 10 fetal and neonatal rhesus macaques were studied for membrane characteristics. Spontaneous rosette formation with sheep erythrocytes, a characteristic of human T lymphocytes, was evaluated. The presence of membrane-bound immunoglobulin and surface receptors for fixed complement was measured, using fluorescent antibody techniques and erythrocyte-antibody-complement rosettes, respectively. The mean percentages +/- 1 standard error of the lymphocyte markers in the peripheral blood lymphocytes from the macaques were: spontaneous rosettes, 63 +/- 1.0; erythrocyte-antibody-complement rosettes, 14.9 +/- 1.2; and membrane immunoglobulin-positive cells, 21.9 +/- 2.2. These values are very similar to values reported for human beings.
AB - Peripheral blood lymphocytes from 37 healthy rhesus macaques (Macaca mulatta) and thymocytes from 10 fetal and neonatal rhesus macaques were studied for membrane characteristics. Spontaneous rosette formation with sheep erythrocytes, a characteristic of human T lymphocytes, was evaluated. The presence of membrane-bound immunoglobulin and surface receptors for fixed complement was measured, using fluorescent antibody techniques and erythrocyte-antibody-complement rosettes, respectively. The mean percentages +/- 1 standard error of the lymphocyte markers in the peripheral blood lymphocytes from the macaques were: spontaneous rosettes, 63 +/- 1.0; erythrocyte-antibody-complement rosettes, 14.9 +/- 1.2; and membrane immunoglobulin-positive cells, 21.9 +/- 2.2. These values are very similar to values reported for human beings.
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UR - http://www.scopus.com/inward/citedby.url?scp=0017479842&partnerID=8YFLogxK
M3 - Article
C2 - 322554
AN - SCOPUS:0017479842
VL - 38
SP - 503
EP - 507
JO - American Journal of Veterinary Research
JF - American Journal of Veterinary Research
SN - 0002-9645
IS - 4
ER -