Immunologic factors related to survival and performance in neonatal swine.

J. W. Tyler, James S Cullor, Mark Thurmond, V. L. Douglas, K. M. Parker

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Logistic regression was used to develop models predicting preweaning survival in 334 neonatal swine. Measured risk factors included birth weight, litter size (live born), dam parity, serum IgG concentration, serum ELISA titers recognizing common gram-negative core antigens, and serum concentrations of the third component of complement. Larger birth weights were associated with increased probability of preweaning survival. The highest mortality was observed in litters with more than 12 pigs. Pigs with serum concentration of the third component of complement (C3) in the lowest stratum, less than 20% adult pooled C3 standard (APC3), had reduced mortality, compared with high (greater than 38% APC3) and middle (20 to 38% APC3) groups. Associations between all other variables, including total serum IgG concentration and preweaning survival were not significant. Few pigs had hypogammaglobulinemia, less than 3% of the study population had serum IgG concentrations less than 1 g/dl. Of all measured variables, only birth weight and dam parity were significant predictors of preweaning gain. Larger pigs and pigs born to third or greater parity dams had more preweaning gain than other pigs.

Original languageEnglish (US)
Pages (from-to)1400-1406
Number of pages7
JournalAmerican Journal of Veterinary Research
Issue number9
StatePublished - Sep 1990

ASJC Scopus subject areas

  • veterinary(all)


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