Immunoglobulin A monoclonal gammopathy in two horses with multiple myeloma

Nicola Pusterla, B. A. Stacy, William Vernau, H. E V De Cock, K G Magdesian

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The clinical findings in two horses with secretory multiple myeloma and secondary immunoglobulin A (IgA) monoclonal gammopathy were non-specific and included weight loss, pale mucous membranes, limb oedema and bacterial respiratory tract infection. Consistent laboratory abnormalities included hyperproteinaemia, hyperglobulinaemia, hypoalbuminaemia and hypercalcaemia. The diagnosis was based on the presence of IgA monoclonal gammopathy in serum and urine and bone marrow plasmacytosis (>10 per cent). One horse was euthanased; it had neoplastic plasma cell infiltrates in its kidneys, spleen, liver, bone marrow, myocardium and adrenal glands. The other horse was treated for a bacterial pneumonia and was still alive six months after it was first examined.

Original languageEnglish (US)
Pages (from-to)19-23
Number of pages5
JournalVeterinary Record
Volume155
Issue number1
StatePublished - Jul 3 2004

ASJC Scopus subject areas

  • veterinary(all)

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