Immunochemical techniques for multianalyte analysis of chemical residues in food and the environment: A review

Yong Fang Li, Yuan Ming Sun, Hong Tao Lei, Hong Wang, Yu Dong Shen, Jin Yi Yang, Zhen Lin Xu, Ross C. Beier, Shirley Gee, Bruce D. Hammock, Zhanhui Wang, Xiulan Sun

Research output: Contribution to journalReview article

64 Scopus citations

Abstract

Immunoassay is an emerging technique that has been used in the fields of food and environmental analysis to monitor and control hazardous residues. Multianalyte immunoassays (MAIAs) are favored because they can simultaneously determine several targets in a single test. In this review, an overview of various formats for the MAIA is given. New trends on how to produce antibodies, how to improve antibody specificity and how to manipulate assay formats to obtain the desired multi-analysis schemes are summarized. Finally, the limitations and prospects of MAIAs are discussed.

Original languageEnglish (US)
Pages (from-to)25-40
Number of pages16
JournalTrAC - Trends in Analytical Chemistry
Volume88
DOIs
StatePublished - Mar 1 2017

Keywords

  • Antibody
  • Environmental
  • Food
  • Immunoassay
  • Multianalyte analysis

ASJC Scopus subject areas

  • Analytical Chemistry
  • Environmental Chemistry
  • Spectroscopy

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    Li, Y. F., Sun, Y. M., Lei, H. T., Wang, H., Shen, Y. D., Yang, J. Y., Xu, Z. L., Beier, R. C., Gee, S., Hammock, B. D., Wang, Z., & Sun, X. (2017). Immunochemical techniques for multianalyte analysis of chemical residues in food and the environment: A review. TrAC - Trends in Analytical Chemistry, 88, 25-40. https://doi.org/10.1016/j.trac.2016.12.010