Immunochemical techniques for environmental analysis II. Antibody production and immunoassay development

Maria Pilar Marco, Shirley Gee, Bruce D. Hammock

Research output: Contribution to journalArticle

147 Scopus citations

Abstract

Antibody production is the key step of any immunochemical technique. The antibody determines to a large extent the specificity and sensitivity of the resulting immunochemical technique. These features may be modulated by judicious design of the immunogen and by rational immunoassay development. Criteria for hapten design and the steps involved in the obtention of antibodies and the development of competitive assays are described.

Original languageEnglish (US)
Pages (from-to)415-425
Number of pages11
JournalTrends in Analytical Chemistry
Volume14
Issue number8
DOIs
StatePublished - 1995

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy
  • Environmental Chemistry

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