Immunochemical techniques for environmental analysis II. Antibody production and immunoassay development

Maria Pilar Marco, Shirley Gee, Bruce D. Hammock

Research output: Contribution to journalArticle

147 Citations (Scopus)

Abstract

Antibody production is the key step of any immunochemical technique. The antibody determines to a large extent the specificity and sensitivity of the resulting immunochemical technique. These features may be modulated by judicious design of the immunogen and by rational immunoassay development. Criteria for hapten design and the steps involved in the obtention of antibodies and the development of competitive assays are described.

Original languageEnglish (US)
Pages (from-to)415-425
Number of pages11
JournalTrends in Analytical Chemistry
Volume14
Issue number8
DOIs
StatePublished - 1995

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immunoassay
antibody
Antibodies
Haptens
Assays
assay
environmental analysis
Environmental analysis

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy
  • Environmental Chemistry

Cite this

Immunochemical techniques for environmental analysis II. Antibody production and immunoassay development. / Marco, Maria Pilar; Gee, Shirley; Hammock, Bruce D.

In: Trends in Analytical Chemistry, Vol. 14, No. 8, 1995, p. 415-425.

Research output: Contribution to journalArticle

Marco, Maria Pilar ; Gee, Shirley ; Hammock, Bruce D. / Immunochemical techniques for environmental analysis II. Antibody production and immunoassay development. In: Trends in Analytical Chemistry. 1995 ; Vol. 14, No. 8. pp. 415-425.
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