Immunization of mice against Streptococcus suis serotype 2 infections using a live avirulent strain

S. Quessy, J. D. Dubreuil, Robert Higgins

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

In this study, the IgG response of mice injected with two virulent strains and one avirulent Streptococcus suis capsular type 2 strain was compared by Western blotting. The serum from mice immunized against the avirulent strain could recognize most proteins of the various strains tested and similar results were obtained with serum from mice injected with virulent strains. The live avirulent strain was injected twice (day 0 and 10) to groups of five mice, and four virulent strains from different geographical origins were used to challenge the animals. All mice, except one in one group, survived the challenge. These results suggest that a live avirulent strain could be used for immunization of swine, the natural host.

Original languageEnglish (US)
Pages (from-to)299-301
Number of pages3
JournalCanadian Journal of Veterinary Research
Volume58
Issue number4
StatePublished - Jan 1 1994
Externally publishedYes

Fingerprint

Streptococcus suis
avirulent strains
Immunization
immunization
serotypes
mice
Infection
infection
Serum
Western blotting
Swine
Immunoglobulin G
Western Blotting
Serogroup
swine
virulent strains
animals
Proteins
proteins

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Immunization of mice against Streptococcus suis serotype 2 infections using a live avirulent strain. / Quessy, S.; Dubreuil, J. D.; Higgins, Robert.

In: Canadian Journal of Veterinary Research, Vol. 58, No. 4, 01.01.1994, p. 299-301.

Research output: Contribution to journalArticle

@article{4bf2eedf94674ade84747e6516f3b0f5,
title = "Immunization of mice against Streptococcus suis serotype 2 infections using a live avirulent strain",
abstract = "In this study, the IgG response of mice injected with two virulent strains and one avirulent Streptococcus suis capsular type 2 strain was compared by Western blotting. The serum from mice immunized against the avirulent strain could recognize most proteins of the various strains tested and similar results were obtained with serum from mice injected with virulent strains. The live avirulent strain was injected twice (day 0 and 10) to groups of five mice, and four virulent strains from different geographical origins were used to challenge the animals. All mice, except one in one group, survived the challenge. These results suggest that a live avirulent strain could be used for immunization of swine, the natural host.",
author = "S. Quessy and Dubreuil, {J. D.} and Robert Higgins",
year = "1994",
month = "1",
day = "1",
language = "English (US)",
volume = "58",
pages = "299--301",
journal = "Canadian Journal of Veterinary Research",
issn = "0830-9000",
publisher = "Canadian Veterinary Medical Association",
number = "4",

}

TY - JOUR

T1 - Immunization of mice against Streptococcus suis serotype 2 infections using a live avirulent strain

AU - Quessy, S.

AU - Dubreuil, J. D.

AU - Higgins, Robert

PY - 1994/1/1

Y1 - 1994/1/1

N2 - In this study, the IgG response of mice injected with two virulent strains and one avirulent Streptococcus suis capsular type 2 strain was compared by Western blotting. The serum from mice immunized against the avirulent strain could recognize most proteins of the various strains tested and similar results were obtained with serum from mice injected with virulent strains. The live avirulent strain was injected twice (day 0 and 10) to groups of five mice, and four virulent strains from different geographical origins were used to challenge the animals. All mice, except one in one group, survived the challenge. These results suggest that a live avirulent strain could be used for immunization of swine, the natural host.

AB - In this study, the IgG response of mice injected with two virulent strains and one avirulent Streptococcus suis capsular type 2 strain was compared by Western blotting. The serum from mice immunized against the avirulent strain could recognize most proteins of the various strains tested and similar results were obtained with serum from mice injected with virulent strains. The live avirulent strain was injected twice (day 0 and 10) to groups of five mice, and four virulent strains from different geographical origins were used to challenge the animals. All mice, except one in one group, survived the challenge. These results suggest that a live avirulent strain could be used for immunization of swine, the natural host.

UR - http://www.scopus.com/inward/record.url?scp=0028092115&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028092115&partnerID=8YFLogxK

M3 - Article

C2 - 7889463

AN - SCOPUS:0028092115

VL - 58

SP - 299

EP - 301

JO - Canadian Journal of Veterinary Research

JF - Canadian Journal of Veterinary Research

SN - 0830-9000

IS - 4

ER -