Abstract
Temperature-sensitive (TS) mutants of the S6 strain of Mycoplasma gallisepticum (MG) were used to immunize newly hatched chickens. Immunized chickens developed antibodies to the wild-type (WT) S6 strain as demonstrated by serologic tests. MG was recovered from nasal cavities but not from the lower respiratory tract of the immunized chicks. Three weeks after intranasal immunization, chickens were challenged via the air sacs with the virulent S6 strain. Immunized chickens were significantly better protected from development of air-sac lesions than were controls.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 803-812 |
| Number of pages | 10 |
| Journal | Avian Diseases |
| Volume | 27 |
| Issue number | 3 |
| State | Published - Jul 1983 |
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- Cancer Research
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Immunization of chickens with temperature-sensitive mutants of Mycoplasma gallisepticum. / Lam, K. M.; Lin, W. Q.; Yamamoto, R.; Farver, T. B.
In: Avian Diseases, Vol. 27, No. 3, 07.1983, p. 803-812.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Immunization of chickens with temperature-sensitive mutants of Mycoplasma gallisepticum.
AU - Lam, K. M.
AU - Lin, W. Q.
AU - Yamamoto, R.
AU - Farver, T. B.
PY - 1983/7
Y1 - 1983/7
N2 - Temperature-sensitive (TS) mutants of the S6 strain of Mycoplasma gallisepticum (MG) were used to immunize newly hatched chickens. Immunized chickens developed antibodies to the wild-type (WT) S6 strain as demonstrated by serologic tests. MG was recovered from nasal cavities but not from the lower respiratory tract of the immunized chicks. Three weeks after intranasal immunization, chickens were challenged via the air sacs with the virulent S6 strain. Immunized chickens were significantly better protected from development of air-sac lesions than were controls.
AB - Temperature-sensitive (TS) mutants of the S6 strain of Mycoplasma gallisepticum (MG) were used to immunize newly hatched chickens. Immunized chickens developed antibodies to the wild-type (WT) S6 strain as demonstrated by serologic tests. MG was recovered from nasal cavities but not from the lower respiratory tract of the immunized chicks. Three weeks after intranasal immunization, chickens were challenged via the air sacs with the virulent S6 strain. Immunized chickens were significantly better protected from development of air-sac lesions than were controls.
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UR - http://www.scopus.com/inward/citedby.url?scp=0020789036&partnerID=8YFLogxK
M3 - Article
C2 - 6227317
AN - SCOPUS:0020789036
VL - 27
SP - 803
EP - 812
JO - Avian Diseases
JF - Avian Diseases
SN - 0005-2086
IS - 3
ER -