Immunization of chickens with temperature-sensitive mutants of Mycoplasma gallisepticum.

K. M. Lam, W. Q. Lin, R. Yamamoto, T. B. Farver

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Temperature-sensitive (TS) mutants of the S6 strain of Mycoplasma gallisepticum (MG) were used to immunize newly hatched chickens. Immunized chickens developed antibodies to the wild-type (WT) S6 strain as demonstrated by serologic tests. MG was recovered from nasal cavities but not from the lower respiratory tract of the immunized chicks. Three weeks after intranasal immunization, chickens were challenged via the air sacs with the virulent S6 strain. Immunized chickens were significantly better protected from development of air-sac lesions than were controls.

Original languageEnglish (US)
Pages (from-to)803-812
Number of pages10
JournalAvian Diseases
Volume27
Issue number3
StatePublished - Jul 1983

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Mycoplasma gallisepticum
S 6
Chickens
Immunization
immunization
Air Sacs
chickens
mutants
air sacs
Temperature
temperature
nasal cavity
Nasal Cavity
Serologic Tests
immunologic techniques
respiratory system
lesions (animal)
Respiratory System
chicks
antibodies

ASJC Scopus subject areas

  • Cancer Research

Cite this

Immunization of chickens with temperature-sensitive mutants of Mycoplasma gallisepticum. / Lam, K. M.; Lin, W. Q.; Yamamoto, R.; Farver, T. B.

In: Avian Diseases, Vol. 27, No. 3, 07.1983, p. 803-812.

Research output: Contribution to journalArticle

Lam, K. M. ; Lin, W. Q. ; Yamamoto, R. ; Farver, T. B. / Immunization of chickens with temperature-sensitive mutants of Mycoplasma gallisepticum. In: Avian Diseases. 1983 ; Vol. 27, No. 3. pp. 803-812.
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