Immunity to bovine reproductive infections

Lynette B. Corbeil, Robert Bondurant

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

Protective immune responses in the genital tract are robust, as shown by convalescent and vaccine-induced immunity. Systemic immunity is crucial for systemic infections that result in reproductive failure (such as brucellosis, leptospirosis, and the systemic forms of C. fetus and H. somnus infection). Although IgA responses can protect against sexually transmitted or venereal infections, systemically induced IgG antibody responses also protect. IgA responses can be induced by immunization of the genital tract, where inductive sites develop after antigenic stimulation. The common mucosal immune system can also be used to induce a genital IgA response, as shown by intranasal vaccination. Lastly, it is necessary to determine which antigens of each infectious agent are protective and which types of immune responses protect best.

Original languageEnglish (US)
Pages (from-to)567-583
Number of pages17
JournalThe Veterinary clinics of North America. Food animal practice
Volume17
Issue number3
DOIs
StatePublished - Jan 1 2001

Fingerprint

Immunoglobulin A
genitalia
Immunity
immunity
cattle
Infection
immune response
infection
Protective Agents
Leptospirosis
Brucellosis
leptospirosis
brucellosis
Antibody Formation
fetus
immune system
Immune System
Immunization
immunization
Vaccination

ASJC Scopus subject areas

  • Food Animals

Cite this

Immunity to bovine reproductive infections. / Corbeil, Lynette B.; Bondurant, Robert.

In: The Veterinary clinics of North America. Food animal practice, Vol. 17, No. 3, 01.01.2001, p. 567-583.

Research output: Contribution to journalReview article

@article{8e8c7b478bbc43198e099a339cb4d2ee,
title = "Immunity to bovine reproductive infections",
abstract = "Protective immune responses in the genital tract are robust, as shown by convalescent and vaccine-induced immunity. Systemic immunity is crucial for systemic infections that result in reproductive failure (such as brucellosis, leptospirosis, and the systemic forms of C. fetus and H. somnus infection). Although IgA responses can protect against sexually transmitted or venereal infections, systemically induced IgG antibody responses also protect. IgA responses can be induced by immunization of the genital tract, where inductive sites develop after antigenic stimulation. The common mucosal immune system can also be used to induce a genital IgA response, as shown by intranasal vaccination. Lastly, it is necessary to determine which antigens of each infectious agent are protective and which types of immune responses protect best.",
author = "Corbeil, {Lynette B.} and Robert Bondurant",
year = "2001",
month = "1",
day = "1",
doi = "10.1016/S0749-0720(15)30007-4",
language = "English (US)",
volume = "17",
pages = "567--583",
journal = "Veterinary Clinics of North America - Food Animal Practice",
issn = "0749-0720",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Immunity to bovine reproductive infections

AU - Corbeil, Lynette B.

AU - Bondurant, Robert

PY - 2001/1/1

Y1 - 2001/1/1

N2 - Protective immune responses in the genital tract are robust, as shown by convalescent and vaccine-induced immunity. Systemic immunity is crucial for systemic infections that result in reproductive failure (such as brucellosis, leptospirosis, and the systemic forms of C. fetus and H. somnus infection). Although IgA responses can protect against sexually transmitted or venereal infections, systemically induced IgG antibody responses also protect. IgA responses can be induced by immunization of the genital tract, where inductive sites develop after antigenic stimulation. The common mucosal immune system can also be used to induce a genital IgA response, as shown by intranasal vaccination. Lastly, it is necessary to determine which antigens of each infectious agent are protective and which types of immune responses protect best.

AB - Protective immune responses in the genital tract are robust, as shown by convalescent and vaccine-induced immunity. Systemic immunity is crucial for systemic infections that result in reproductive failure (such as brucellosis, leptospirosis, and the systemic forms of C. fetus and H. somnus infection). Although IgA responses can protect against sexually transmitted or venereal infections, systemically induced IgG antibody responses also protect. IgA responses can be induced by immunization of the genital tract, where inductive sites develop after antigenic stimulation. The common mucosal immune system can also be used to induce a genital IgA response, as shown by intranasal vaccination. Lastly, it is necessary to determine which antigens of each infectious agent are protective and which types of immune responses protect best.

UR - http://www.scopus.com/inward/record.url?scp=0035513671&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035513671&partnerID=8YFLogxK

U2 - 10.1016/S0749-0720(15)30007-4

DO - 10.1016/S0749-0720(15)30007-4

M3 - Review article

C2 - 11692509

AN - SCOPUS:0035513671

VL - 17

SP - 567

EP - 583

JO - Veterinary Clinics of North America - Food Animal Practice

JF - Veterinary Clinics of North America - Food Animal Practice

SN - 0749-0720

IS - 3

ER -