TY - JOUR
T1 - Immunity, host physiology, and behaviour in infected vectors
AU - Murdock, Courtney C.
AU - Luckhart, Shirley
AU - Cator, Lauren J.
PY - 2017/4/1
Y1 - 2017/4/1
N2 - When infection alters host behaviour such that the pathogen benefits, the behaviour is termed a manipulation. There are several examples of this fascinating phenomenon in many different systems. Vector-borne diseases are no exception. In some instances, as the term implies, pathogens directly interfere with host processes to control behaviour. However, host response to infection and host physiology are likely to play important roles in these phenotypes. We highlight the importance of considering host response and physiology from recent work on altered host-seeking in malaria parasite-infected mosquitoes and argue that this general approach will provide useful insights across vector-borne disease systems.
AB - When infection alters host behaviour such that the pathogen benefits, the behaviour is termed a manipulation. There are several examples of this fascinating phenomenon in many different systems. Vector-borne diseases are no exception. In some instances, as the term implies, pathogens directly interfere with host processes to control behaviour. However, host response to infection and host physiology are likely to play important roles in these phenotypes. We highlight the importance of considering host response and physiology from recent work on altered host-seeking in malaria parasite-infected mosquitoes and argue that this general approach will provide useful insights across vector-borne disease systems.
UR - http://www.scopus.com/inward/record.url?scp=85015974587&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85015974587&partnerID=8YFLogxK
U2 - 10.1016/j.cois.2017.03.001
DO - 10.1016/j.cois.2017.03.001
M3 - Review article
AN - SCOPUS:85015974587
VL - 20
SP - 28
EP - 33
JO - Current Opinion in Insect Science
JF - Current Opinion in Insect Science
SN - 2214-5745
ER -