Immune responses to Mycoplasma bovis vaccination and experimental infection in the bovine mammary gland.

J. T. Boothby, C. E. Schore, D. E. Jasper, Bennie Osburn, C. B. Thomas

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

This study characterized the immune responses in four vaccinated and four control cows in response to vaccination and experimental intramammary inoculation with Mycoplasma bovis. Specific antibody responses occurred in serum and milk in response to vaccination and experimental infection. Lymphocytes from peripheral blood, but not from the mammary gland of vaccinated cows had increased responsiveness to mitogens. No lymphocytes tested were responsive to M. bovis antigen. Both vaccination and experimental infection resulted in skin test reactivity. These results imply that vaccination results in immune responses which may alter the course of experimental M. bovis mastitis, but may contribute to cellular inflammation.

Original languageEnglish (US)
Pages (from-to)355-359
Number of pages5
JournalCanadian journal of veterinary research = Revue canadienne de recherche veterinaire
Volume52
Issue number3
StatePublished - Jul 1 1988

ASJC Scopus subject areas

  • veterinary(all)

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