Immune Responses and B Complex Associated Resistance to Infectious Bronchitis Virus in Chickens

Rodrigo A. Gallardo, Ana P. Da Silva

Research output: Contribution to journalReview articlepeer-review

Abstract

SUMMARY. Infectious bronchitis (IB) continues to be a global threat to poultry producers. The chicken major histocompatibility complex (MHC) or chicken B complex is compact, restricted to a single chromosome, and approximately 20-fold smaller than the mammalian MHC. Abundant evidence indicates that the B complex is strongly associated with resistance to various infectious agents in chickens. While an association between different B haplotypes and resistance against several bacterial and viral diseases has been established, additional work needs to be performed on the association between the B complex and resistance to IB viruses (IBV). Here, some of the available knowledge on genetic resistance to viral poultry diseases conferred by the chicken B locus is reviewed. IBV immune responses and resistance associated with differing B haplotype chicken lines are reviewed and discussed herein.

Original languageEnglish (US)
Pages (from-to)610-616
Number of pages7
JournalAvian diseases
Volume65
Issue number4
DOIs
StatePublished - Nov 18 2021
Externally publishedYes

Keywords

  • IBV
  • immune responses
  • MHC
  • relative resistance

ASJC Scopus subject areas

  • Food Animals
  • Animal Science and Zoology
  • Immunology and Microbiology(all)

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