Immune response of the llama (Lama glama) to tetanus toxoid vaccination.

Joanne R Paul-Murphy, Laurel J Gershwin, E. F. Thatcher, M. E. Fowler, W. H. Habig

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

An ELISA was developed to measure serum concentrations of tetanus toxoid-specific immunoglobulins. The titers obtained with this assay were compatible with those obtained by the standard mouse toxin-neutralization test. Serum samples from 123 llamas were analyzed for ELISA titers to tetanus toxoid. Of the 82 vaccinated adults, 75 (91%) had titers greater than or equal to 1:50. The vaccination status and titers of weanlings and juveniles (3 to 12 months old) varied; of the 21 vaccinated, 17 (81%) had titers greater than or equal to 1:50 and 7 of 9 (78%) unvaccinated llamas had titers less than 1:50. The ELISA titers of unvaccinated llamas less than 8 weeks old (crias) were matched with the maternal titers. All crias with titers less than 1:50 had dams with titers greater than or equal to 1:50.

Original languageEnglish (US)
Pages (from-to)1279-1281
Number of pages3
JournalAmerican Journal of Veterinary Research
Volume50
Issue number8
StatePublished - Aug 1989

ASJC Scopus subject areas

  • veterinary(all)

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