Immune-based therapies for sarcoma

Robin L. Jones, Seth M. Pollack, Elizabeth T. Loggers, Eve Rodler, Cassian Yee

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Immunotherapy has shown promise in a number of tumor types, but its exact role in sarcoma remains to be defined. Advanced bone and soft tissue sarcomas are challenging diseases to treat with an unmet need for effective systemic therapy. Previous reports have suggested that immune-based treatments may be effective in sarcoma, but such approaches have not yet become part of standard clinical practice. A number of sarcoma subtypes express targets known as cancer testis antigens and hence may be excellent targets for immunotherapy. This paper will focus on the recent advances and understanding of cancer testis antigens in sarcoma and also clinical data of immunotherapeutic approaches in these diseases.

Original languageEnglish (US)
Article number438940
JournalSarcoma
Volume2011
DOIs
StatePublished - 2011
Externally publishedYes

Fingerprint

Sarcoma
Testicular Neoplasms
Immunotherapy
Therapeutics
Antigens
Bone and Bones
Neoplasms

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Jones, R. L., Pollack, S. M., Loggers, E. T., Rodler, E., & Yee, C. (2011). Immune-based therapies for sarcoma. Sarcoma, 2011, [438940]. https://doi.org/10.1155/2011/438940

Immune-based therapies for sarcoma. / Jones, Robin L.; Pollack, Seth M.; Loggers, Elizabeth T.; Rodler, Eve; Yee, Cassian.

In: Sarcoma, Vol. 2011, 438940, 2011.

Research output: Contribution to journalArticle

Jones, RL, Pollack, SM, Loggers, ET, Rodler, E & Yee, C 2011, 'Immune-based therapies for sarcoma', Sarcoma, vol. 2011, 438940. https://doi.org/10.1155/2011/438940
Jones RL, Pollack SM, Loggers ET, Rodler E, Yee C. Immune-based therapies for sarcoma. Sarcoma. 2011;2011. 438940. https://doi.org/10.1155/2011/438940
Jones, Robin L. ; Pollack, Seth M. ; Loggers, Elizabeth T. ; Rodler, Eve ; Yee, Cassian. / Immune-based therapies for sarcoma. In: Sarcoma. 2011 ; Vol. 2011.
@article{3431304e77cc4d4c930d369e27629fff,
title = "Immune-based therapies for sarcoma",
abstract = "Immunotherapy has shown promise in a number of tumor types, but its exact role in sarcoma remains to be defined. Advanced bone and soft tissue sarcomas are challenging diseases to treat with an unmet need for effective systemic therapy. Previous reports have suggested that immune-based treatments may be effective in sarcoma, but such approaches have not yet become part of standard clinical practice. A number of sarcoma subtypes express targets known as cancer testis antigens and hence may be excellent targets for immunotherapy. This paper will focus on the recent advances and understanding of cancer testis antigens in sarcoma and also clinical data of immunotherapeutic approaches in these diseases.",
author = "Jones, {Robin L.} and Pollack, {Seth M.} and Loggers, {Elizabeth T.} and Eve Rodler and Cassian Yee",
year = "2011",
doi = "10.1155/2011/438940",
language = "English (US)",
volume = "2011",
journal = "Sarcoma",
issn = "1357-714X",
publisher = "Hindawi Publishing Corporation",

}

TY - JOUR

T1 - Immune-based therapies for sarcoma

AU - Jones, Robin L.

AU - Pollack, Seth M.

AU - Loggers, Elizabeth T.

AU - Rodler, Eve

AU - Yee, Cassian

PY - 2011

Y1 - 2011

N2 - Immunotherapy has shown promise in a number of tumor types, but its exact role in sarcoma remains to be defined. Advanced bone and soft tissue sarcomas are challenging diseases to treat with an unmet need for effective systemic therapy. Previous reports have suggested that immune-based treatments may be effective in sarcoma, but such approaches have not yet become part of standard clinical practice. A number of sarcoma subtypes express targets known as cancer testis antigens and hence may be excellent targets for immunotherapy. This paper will focus on the recent advances and understanding of cancer testis antigens in sarcoma and also clinical data of immunotherapeutic approaches in these diseases.

AB - Immunotherapy has shown promise in a number of tumor types, but its exact role in sarcoma remains to be defined. Advanced bone and soft tissue sarcomas are challenging diseases to treat with an unmet need for effective systemic therapy. Previous reports have suggested that immune-based treatments may be effective in sarcoma, but such approaches have not yet become part of standard clinical practice. A number of sarcoma subtypes express targets known as cancer testis antigens and hence may be excellent targets for immunotherapy. This paper will focus on the recent advances and understanding of cancer testis antigens in sarcoma and also clinical data of immunotherapeutic approaches in these diseases.

UR - http://www.scopus.com/inward/record.url?scp=79953281185&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79953281185&partnerID=8YFLogxK

U2 - 10.1155/2011/438940

DO - 10.1155/2011/438940

M3 - Article

C2 - 21331153

AN - SCOPUS:79953281185

VL - 2011

JO - Sarcoma

JF - Sarcoma

SN - 1357-714X

M1 - 438940

ER -