Immune-based therapies for sarcoma

Robin L. Jones, Seth M. Pollack, Elizabeth T. Loggers, Eve Rodler, Cassian Yee

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Immunotherapy has shown promise in a number of tumor types, but its exact role in sarcoma remains to be defined. Advanced bone and soft tissue sarcomas are challenging diseases to treat with an unmet need for effective systemic therapy. Previous reports have suggested that immune-based treatments may be effective in sarcoma, but such approaches have not yet become part of standard clinical practice. A number of sarcoma subtypes express targets known as cancer testis antigens and hence may be excellent targets for immunotherapy. This paper will focus on the recent advances and understanding of cancer testis antigens in sarcoma and also clinical data of immunotherapeutic approaches in these diseases.

Original languageEnglish (US)
Article number438940
StatePublished - 2011
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging


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