Abstract
Cryptococcus neoformans cells must cross the blood-brain barrier prior to invading the central nervous system. Here we demonstrate that the immortalized human brain endothelial cell line HCMEC/D3 is a useful alternative to primary brain endothelial cells as a model of the blood-brain barrier for studies of central nervous system infection.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1803-1807 |
| Number of pages | 5 |
| Journal | Eukaryotic Cell |
| Volume | 8 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 2009 |
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ASJC Scopus subject areas
- Microbiology
- Molecular Biology
Cite this
Immortalized human brain endothelial cell line HCMEC/D3 as a model of the blood-brain barrier facilitates in vitro studies of central nervous system infection by cryptococcus neoformans. / Vu, Kiem; Weksler, Babette; Romero, Ignacio; Couraud, Pierre Olivier; Gelli, Angela C.
In: Eukaryotic Cell, Vol. 8, No. 11, 11.2009, p. 1803-1807.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Immortalized human brain endothelial cell line HCMEC/D3 as a model of the blood-brain barrier facilitates in vitro studies of central nervous system infection by cryptococcus neoformans
AU - Vu, Kiem
AU - Weksler, Babette
AU - Romero, Ignacio
AU - Couraud, Pierre Olivier
AU - Gelli, Angela C
PY - 2009/11
Y1 - 2009/11
N2 - Cryptococcus neoformans cells must cross the blood-brain barrier prior to invading the central nervous system. Here we demonstrate that the immortalized human brain endothelial cell line HCMEC/D3 is a useful alternative to primary brain endothelial cells as a model of the blood-brain barrier for studies of central nervous system infection.
AB - Cryptococcus neoformans cells must cross the blood-brain barrier prior to invading the central nervous system. Here we demonstrate that the immortalized human brain endothelial cell line HCMEC/D3 is a useful alternative to primary brain endothelial cells as a model of the blood-brain barrier for studies of central nervous system infection.
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UR - http://www.scopus.com/inward/citedby.url?scp=72449202243&partnerID=8YFLogxK
U2 - 10.1128/EC.00240-09
DO - 10.1128/EC.00240-09
M3 - Article
C2 - 19767445
AN - SCOPUS:72449202243
VL - 8
SP - 1803
EP - 1807
JO - Eukaryotic Cell
JF - Eukaryotic Cell
SN - 1535-9778
IS - 11
ER -