Abstract
Cryptococcus neoformans cells must cross the blood-brain barrier prior to invading the central nervous system. Here we demonstrate that the immortalized human brain endothelial cell line HCMEC/D3 is a useful alternative to primary brain endothelial cells as a model of the blood-brain barrier for studies of central nervous system infection.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1803-1807 |
| Number of pages | 5 |
| Journal | Eukaryotic Cell |
| Volume | 8 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 2009 |
ASJC Scopus subject areas
- Microbiology
- Molecular Biology
Fingerprint Dive into the research topics of 'Immortalized human brain endothelial cell line HCMEC/D3 as a model of the blood-brain barrier facilitates in vitro studies of central nervous system infection by cryptococcus neoformans'. Together they form a unique fingerprint.
Cite this
Vu, K., Weksler, B., Romero, I., Couraud, P. O., & Gelli, A. C. (2009). Immortalized human brain endothelial cell line HCMEC/D3 as a model of the blood-brain barrier facilitates in vitro studies of central nervous system infection by cryptococcus neoformans. Eukaryotic Cell, 8(11), 1803-1807. https://doi.org/10.1128/EC.00240-09