Imaging of the human choroid with a 1.7 MHz A-scan rate FDML swept source OCT system

I. Gorczynska, J. V. Migacz, Ravi Jonnal, Robert Zawadzki, R. Poddar, John S Werner

Research output: Chapter in Book/Report/Conference proceedingConference contribution

14 Scopus citations

Abstract

We demonstrate OCT angiography (OCTA) and Doppler OCT imaging of the choroid in the eyes of two healthy volunteers and in a geographic atrophy case. We show that visualization of specific choroidal layers requires selection of appropriate OCTA methods. We investigate how imaging speed, B-scan averaging and scanning density influence visualization of various choroidal vessels. We introduce spatial power spectrum analysis of OCT en face angiographic projections as a method of quantitative analysis of choroicapillaris morphology. We explore the possibility of Doppler OCT imaging to provide information about directionality of blood flow in choroidal vessels. To achieve these goals, we have developed OCT systems utilizing an FDML laser operating at 1.7 MHz sweep rate, at 1060 nm center wavelength, and with 7.5 μm axial imaging resolution. A correlation mapping OCA method was implemented for visualization of the vessels. Joint Spectral and Time domain OCT (STdOCT) technique was used for Doppler OCT imaging.

Original languageEnglish (US)
Title of host publicationOpthalmic Technologies XXVII
PublisherSPIE
Volume10045
ISBN (Electronic)9781510605312
DOIs
StatePublished - 2017
Event27th Conference on Ophthalmic Technologies - San Francisco, United States
Duration: Jan 28 2017Jan 29 2017

Other

Other27th Conference on Ophthalmic Technologies
CountryUnited States
CitySan Francisco
Period1/28/171/29/17

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Keywords

  • Choriocapillaris
  • Choroid
  • Doppler OCT
  • Flow imaging
  • Fourier-domain mode-locked laser
  • OCT Angiography
  • Swept-source OCT

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Gorczynska, I., Migacz, J. V., Jonnal, R., Zawadzki, R., Poddar, R., & Werner, J. S. (2017). Imaging of the human choroid with a 1.7 MHz A-scan rate FDML swept source OCT system. In Opthalmic Technologies XXVII (Vol. 10045). [1004510] SPIE. https://doi.org/10.1117/12.2251704