Ikarugamycin: Total synthesis of the decahydro-as-indacene portion

Mark J. Kurth, Dennis H. Burns, Michael J. O'Brien

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

An efficient, stereoselective synthesis of octahydro-as-indacenone 2, the carbocycle fragment of the antibiotic ikarugamycin, is described. The prominent step in this sequence is an intramolecular Diels-Alder reaction, which establishes the relative stereochemistry of 2.

Original languageEnglish (US)
Pages (from-to)731-733
Number of pages3
JournalJournal of Organic Chemistry
Volume49
Issue number4
StatePublished - 1984

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Stereochemistry
Anti-Bacterial Agents
ikarugamycin

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Kurth, M. J., Burns, D. H., & O'Brien, M. J. (1984). Ikarugamycin: Total synthesis of the decahydro-as-indacene portion. Journal of Organic Chemistry, 49(4), 731-733.

Ikarugamycin : Total synthesis of the decahydro-as-indacene portion. / Kurth, Mark J.; Burns, Dennis H.; O'Brien, Michael J.

In: Journal of Organic Chemistry, Vol. 49, No. 4, 1984, p. 731-733.

Research output: Contribution to journalArticle

Kurth, MJ, Burns, DH & O'Brien, MJ 1984, 'Ikarugamycin: Total synthesis of the decahydro-as-indacene portion', Journal of Organic Chemistry, vol. 49, no. 4, pp. 731-733.
Kurth, Mark J. ; Burns, Dennis H. ; O'Brien, Michael J. / Ikarugamycin : Total synthesis of the decahydro-as-indacene portion. In: Journal of Organic Chemistry. 1984 ; Vol. 49, No. 4. pp. 731-733.
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