Idiopathic Localized Eosinophilic Synovitis in a Cat

Deborah C. Silverstein, Frederick S. Almy, Joseph G. Zinkl, Mary M Christopher

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


A 4-year-old male castrated Seal Point Himalayan cat was presented for evaluation of right thoracic limb lameness of 6 weeks duration. Synovial fluid analysis of the swollen right carpal joint revealed a mixed cell synovitis, with a total nucleated cell count of 13,200/μL and 34% eosinophils, A diagnosis of idiopathic localized eosinophilic arthritis was made. Additional clinical and diagnostic findings included mild lymphadenopathy with lymphoid hyperplasia and an antinuclear antibody titer of 1:320. Lack of multisystem involvement made systemic lupus erythematosis unlikely. Immunosuppressive therapy with oral prednisone alleviated the lameness. Eosinophilic synovitis has not previously been reported in cats. An immune-mediated mechanism was likely in this case; however, the exact etiology remains unknown.

Original languageEnglish (US)
Pages (from-to)90-92
Number of pages3
JournalVeterinary Clinical Pathology
Issue number3
StatePublished - 2000


  • Eosinophil
  • Eosinophilic synovitis
  • Feline
  • Immune-mediated arthritis
  • Synovial fluid

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • veterinary(all)


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