Idiopathic hypereosinophilic syndrome in 3 rottweilers

Jane E Sykes, Douglas J. Weiss, Lance C. Buoen, Melissa M. Blauvelt, David W. Hayden

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Three Rottweilers with marked peripheral eosinophilia and infiltration of the liver, spleen, lungs, and bone marrow with eosinophils were diagnosed with idiopathic hypereosinophilic syndrome (IHES). Mean serum immunoglobulin E concentrations were markedly high. On cytogenetic analysis, no evidence of karyotypic abnormalities was found in bone marrow aspirates. Despite an extensive search, no underlying cause for the eosinophilia could be identified. In this study, cytogenetic analysis and measurement of serum IgE concentrations were used to differentiate IHES and eosinophilic leukemia.

Original languageEnglish (US)
Pages (from-to)162-166
Number of pages5
JournalJournal of Veterinary Internal Medicine
Volume15
Issue number2
StatePublished - 2001
Externally publishedYes

Fingerprint

Hypereosinophilic Syndrome
Rottweiler
eosinophilia
cytogenetic analysis
bone marrow
Cytogenetic Analysis
Eosinophilia
immunoglobulin E
Immunoglobulin E
eosinophils
Bone Marrow
leukemia
spleen
lungs
Serum
Eosinophils
liver
Spleen
Lung
Liver

Keywords

  • Cytogenetic analysis
  • Dogs
  • Eosinophilic gastroenteritis
  • Eosinophilic leukemia
  • Immunoglobulin E
  • Splendore-Hoeppli phenomenon

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Sykes, J. E., Weiss, D. J., Buoen, L. C., Blauvelt, M. M., & Hayden, D. W. (2001). Idiopathic hypereosinophilic syndrome in 3 rottweilers. Journal of Veterinary Internal Medicine, 15(2), 162-166.

Idiopathic hypereosinophilic syndrome in 3 rottweilers. / Sykes, Jane E; Weiss, Douglas J.; Buoen, Lance C.; Blauvelt, Melissa M.; Hayden, David W.

In: Journal of Veterinary Internal Medicine, Vol. 15, No. 2, 2001, p. 162-166.

Research output: Contribution to journalArticle

Sykes, JE, Weiss, DJ, Buoen, LC, Blauvelt, MM & Hayden, DW 2001, 'Idiopathic hypereosinophilic syndrome in 3 rottweilers', Journal of Veterinary Internal Medicine, vol. 15, no. 2, pp. 162-166.
Sykes JE, Weiss DJ, Buoen LC, Blauvelt MM, Hayden DW. Idiopathic hypereosinophilic syndrome in 3 rottweilers. Journal of Veterinary Internal Medicine. 2001;15(2):162-166.
Sykes, Jane E ; Weiss, Douglas J. ; Buoen, Lance C. ; Blauvelt, Melissa M. ; Hayden, David W. / Idiopathic hypereosinophilic syndrome in 3 rottweilers. In: Journal of Veterinary Internal Medicine. 2001 ; Vol. 15, No. 2. pp. 162-166.
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