Idiopathic chronic eosinophilic pneumonia in 7 horses

Stephanie A. Bell, C. P. Drew, William D Wilson, Nicola Pusterla

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Background: Idiopathic chronic eosinophilic pneumonia of horses is incompletely described. Objectives: To describe the physical examination, clinicopathologic, histopathologic, and radiographic features and response to corticosteroid treatment of idiopathic chronic eosinophilic pneumonia of horses. Animals: Seven horses with eosinophilic pneumonia. Methods: Retrospective, descriptive study. Results: Anamnesis, clinical signs, and clinicopathologic and radiologic findings in 7 adult horses with histologically confirmed eosinophilic pneumonia were reviewed. The horses were examined for signs of chronic respiratory disease. The horses ranged in age from 8 to 20 years. Significant findings on physical examination included tachypnea and abnormal respiratory sounds. Thoracic radiography revealed severe diffuse interstitial patterns of increased pulmonary density in all horses. There was a predominance of eosinophils in bronchoalveolar lavage fluid (BALF), and 6 of 7 horses had peripheral blood eosinophilia. Lung biopsies revealed eosinophilic infiltrates in all horses. Dexamethasone was administered to 3 horses and resulted in short-term clinical improvement in all three. Conclusions and Clinical Importance: A diagnosis of idiopathic eosinophilic pneumonia should be considered in horses with a history of chronic pulmonary disease, diffuse interstitial pattern of increased pulmonary density on thoracic radiographs, and a predominance of eosinophils in BALF. Horses with this condition may show a temporary response to treatment with dexamethasone.

Original languageEnglish (US)
Pages (from-to)648-653
Number of pages6
JournalJournal of Veterinary Internal Medicine
Volume22
Issue number3
DOIs
StatePublished - May 2008

Keywords

  • Equine
  • Interstitial
  • Pulmonary
  • Respiratory

ASJC Scopus subject areas

  • veterinary(all)

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